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The chemical at hand is not a designer drug
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'''Phenylpiracetam hydrazide''', also known as '''fonturacetam hydrazide''',<ref>{{cite journal|title=International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names: List 63|journal=WHO Drug Information|date=2010|volume=24|issue=1|page=56|url=http://apps.who.int/medicinedocs/documents/s17753en/s17753en.pdf|accessdate=26 November 2015}}</ref> is a [[designer drug]] that is a [[derivative (chemistry)|derivative]] of [[phenylpiracetam]] in which the [[carboxamide|amide]] group is replaced with a [[hydrazide]] group. It was first reported by a Russian research group in 1980 as part of a series of chemical compounds investigated as [[anticonvulsant]]s.<ref name=Glozman>{{cite journal | title = Synthesis and anticonvulsive activity of 4-phenyl-2-pyrrolidinone-1-acetic acid amides |author1=Glozman, O. M. |author2=Morozov, I. S. |author3=Zhmurenko, L. A. |author4=Zagorevskii, V. A. | journal = Khimiko-Farmatsevticheskii Zhurnal | date = 1980 | volume = 14 | issue = 11 | pages = 43–48 | language = Russian}}</ref> In an electroshock test it was found to have an [[Effective dose (pharmacology)|ED<sub>50</sub>]] of 310&nbsp;mg/kg.<ref name=Glozman/>
'''Phenylpiracetam hydrazide''', also known as '''fonturacetam hydrazide''',<ref>{{cite journal|title=International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names: List 63|journal=WHO Drug Information|date=2010|volume=24|issue=1|page=56|url=http://apps.who.int/medicinedocs/documents/s17753en/s17753en.pdf|accessdate=26 November 2015}}</ref> is a putative [[nootropic]] that is a [[derivative (chemistry)|derivative]] of [[phenylpiracetam]] in which the [[carboxamide|amide]] group is replaced with a [[hydrazide]] group. It was first reported by a Russian research group in 1980 as part of a series of chemical compounds investigated as [[anticonvulsant]]s.<ref name=Glozman>{{cite journal | title = Synthesis and anticonvulsive activity of 4-phenyl-2-pyrrolidinone-1-acetic acid amides |author1=Glozman, O. M. |author2=Morozov, I. S. |author3=Zhmurenko, L. A. |author4=Zagorevskii, V. A. | journal = Khimiko-Farmatsevticheskii Zhurnal | date = 1980 | volume = 14 | issue = 11 | pages = 43–48 | language = Russian}}</ref> In an electroshock test it was found to have an [[Effective dose (pharmacology)|ED<sub>50</sub>]] of 310&nbsp;mg/kg.<ref name=Glozman/>


==See also==
==See also==

Revision as of 21:18, 23 February 2018

Phenylpiracetam hydrazide
Clinical data
Trade namesPhenylpiracetam hydrazide
Other namesFonturacetam hydrazide
Pregnancy
category
  • Unknown
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • US: Not FDA approved; unscheduled
Identifiers
  • 2-(2-oxo-4-phenylpyrrolidin-1-yl)acetohydrazide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC12H15N3O2
Molar mass233.27 g/mol g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • c1ccc(cc1)C2CC(=O)N(C2)CC(=O)NN
  • InChI=1S/C12H15N3O2/c13-14-11(16)8-15-7-10(6-12(15)17)9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,14,16) checkY
  • Key:AXQUMNYYLGUJIZ-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Phenylpiracetam hydrazide, also known as fonturacetam hydrazide,[1] is a putative nootropic that is a derivative of phenylpiracetam in which the amide group is replaced with a hydrazide group. It was first reported by a Russian research group in 1980 as part of a series of chemical compounds investigated as anticonvulsants.[2] In an electroshock test it was found to have an ED50 of 310 mg/kg.[2]

See also

References

  1. ^ "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names: List 63" (PDF). WHO Drug Information. 24 (1): 56. 2010. Retrieved 26 November 2015.
  2. ^ a b Glozman, O. M.; Morozov, I. S.; Zhmurenko, L. A.; Zagorevskii, V. A. (1980). "Synthesis and anticonvulsive activity of 4-phenyl-2-pyrrolidinone-1-acetic acid amides". Khimiko-Farmatsevticheskii Zhurnal (in Russian). 14 (11): 43–48.


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