Staphylopine dehydrogenase: Difference between revisions
Appearance
mNo edit summary |
m PCock moved page Draft:Staphylopine dehydrogenase to Staphylopine dehydrogenase: Publishing accepted Articles for creation submission (AFCH 0.9.1) |
(No difference)
|
Revision as of 00:17, 4 December 2019
This article, Staphylopine dehydrogenase, has recently been created via the Articles for creation process. Please check to see if the reviewer has accidentally left this template after accepting the draft and take appropriate action as necessary.
Reviewer tools: Inform author |
In enzymology,a staphylopine synthase (EC 1.5.1.52) is an enzyme that catalyzes NADPH-dependent reductive condensation of pyruvate to the intermediate (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate, which is the last step in the biosynthesis of the metallophore staphylopine[1]. The chemical reaction is
H2O + NADP+ + staphylopine = (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H+ + NADPH + pyruvate[2]
Alternative name(s): staphylopine dehydrogenase.
- ^ Ghssein, G.; Brutesco, C.; Ouerdane, L.; Fojcik, C.; Izaute, A.; Wang, S.; Hajjar, C.; Lobinski, R.; Lemaire, D.; Richaud, P.; Voulhoux, R. (2016-05-26). "Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus". Science. 352 (6289): 1105–1109. doi:10.1126/science.aaf1018. ISSN 0036-8075.
- ^ "cntM - Staphylopine synthase - Staphylococcus aureus (strain Mu50 / ATCC 700699) - cntM gene & protein". www.uniprot.org. Retrieved 2019-12-03.