Talk:Biotin/GA1

GA Review

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Reviewer: HaEr48 (talk · contribs) 21:51, 16 January 2021 (UTC)[reply]

Will look at this. Looking forward to review it while educating myself in another vitamin, David notMD! HaEr48 (talk) 21:51, 16 January 2021 (UTC)[reply]

Initial comments:

Biotin is composed of a ureido ring … any link for ureido?
- No link for ureido ring. I added chem compostion. David notMD (talk) 04:01, 18 January 2021 (UTC)[reply]
  - –N–CO–N– is not a ring, so maybe we should say a ring containing the –N–CO–N– group? HaEr48 (talk) 23:12, 30 January 2021 (UTC)[reply]
Is biotin a single compound or a group of related ones like Vitamin B12?
- Biotin is a single compound. David notMD (talk) 04:01, 18 January 2021 (UTC)[reply]
"The frequency of marginal biotin status is not known" I don't understand this, is it possible to have other wording or add links to improve understanding?
- Deleted, and section revised, with refs added. David notMD (talk) 21:59, 24 January 2021 (UTC)[reply]
The final part of "cofactor biochemistry" seems to be missing citation?
- Completely rewritten and properly referenced. David notMD (talk) 20:36, 25 January 2021 (UTC)[reply]
The lead hints about genetic disorders that cause biotin deficiency, is this the same as the biotinidase deficiency described in #Deficiency? If yes, can you mention it? If not, what are the genetic disorders?
- Details added. David notMD (talk) 02:29, 26 January 2021 (UTC)[reply]
"This enzyme is responsible...": How about "Biotinidase is an enzyme responsible ..." ?

Done. David notMD (talk) 02:29, 26 January 2021 (UTC)[reply]

Biotinidase deficiency seems to be introduced twice, in #Deficiency and in #Metabolic disorders. Maybe better combine them? Or just describe fully in the first mention, and name it without intro in the second usage?
- Resolved. David notMD (talk) 02:34, 26 January 2021 (UTC)[reply]
the proteolytic degradation products of each holocarboxylase: Could you explain what each holocarboxylase refers to?
- Resolved. David notMD (talk) 02:36, 26 January 2021 (UTC)[reply]

Per user talk, will continue reviewing after the nominator finishes making other updates. Thank you! HaEr48 (talk) 22:40, 16 January 2021 (UTC)[reply]

I will address the above bullets and indicate what other sections added or modified.

- Added Diagnosis subsection to Deficiency. David notMD (talk) 04:01, 18 January 2021 (UTC)[reply]
- Added Animals section. David notMD (talk) 17:59, 18 January 2021 (UTC)[reply]
- Changed Bioavailability to Physiology, with subsections on absorption, metabolism, excretion, and conditions that affect biotin status. David notMD (talk) 22:00, 24 January 2021 (UTC)[reply]
- Added Prevalence, diagnosis and treatment subsection to Metabolic disorders. David notMD (talk) 21:28, 26 January 2021 (UTC)[reply]

GA Review

I have found that this article has a minor flaw. It does not fit the Good Article criteria, part 1.a. and 2.b. According to 1.a., the article should be "clear", i.e. precise and have no vague or incomplete statements. It should not contain sentences that provoke further questions merely because these statements are formulated in such a way. According 2.b. of the criteria, an article should not contain "counter-intuitive or controversial statements that are challenged or likely to be challenged", unless there are citations from reliable sources to support these statements. I have found statements that are not clear and are likely to be challenged. See Talk:Biotin#Absorption for details. Maxim Masiutin (talk) 08:18, 29 January 2021 (UTC)[reply]

Maxim Masiutin has move more specific comments about the state of the article to Talk:Biotin and created an Absorption section there, so being addressed there. David notMD (talk) 18:52, 29 January 2021 (UTC)[reply]