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Acanthocyte

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Acanthocytosis in a patient with abetalipoproteinemia.

Acanthocyte, In human biology and medicine, refers to a form of red blood cells with spikes on it.[1]

These cells are coarse and irregularly crenellated resembling many-pointed stars. They are seen on blood films in, among others, abetalipoproteinemia.[2] , liver disease, chorea acanthocytosis, McLeod syndrome and several inherited neurological disorders, such as neuroacanthocytosis.[citation needed]

In veterinary medicine, Acanthocytosis may be seen in dogs with liver disease or hemangiosarcoma.[citation needed]

The term "Echinocyte" (or "burr cell") is similar in meaning to "Acanthocyte", but implies more moderate spiculation.[3]

References

  1. ^ "acanthocyte" at Dorland's Medical Dictionary
  2. ^ Cooper RA, Durocher JR, Leslie MH (1977). "Decreased fluidity of red cell membrane lipids in abetalipoproteinemia". J. Clin. Invest. 60 (1): 115–21. doi:10.1172/JCI108747. PMC 372349. PMID 874076. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  3. ^ "Spiculated cells (echinocytes and acanthocytes) and target cells". Retrieved 2009-06-16.