Talk:Clenbuterol

Pharmacology B‑class Mid‑importance

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Celnbuterol is also gaining attention as a weight-loss pill for the elite crowd. My understanding is that it is - as one might expect - dangerous for human consumption. Wanted to run this by the discussion board before posting the info, as I don't know the exact rules on rumors and gossip going on Wikipedia. --Spesek 02:04, 12 October 2006 (UTC)[reply]

I have also heard of that. Does anyone have any information on this?

Heart problems

I've been hearing about a link between clenbuterol use and cardiac myopathy (which has been explained to me as the thickening of the heart muscle-- not good)... but there's nothing in the article about this link. Web searches uncover lots of articles about clenbuterol and the heart (mostly in medical language that I don't understand). Seems like this article should have some mention of that, somewhere? Can someone with more knowledge of this (I'm not a doctor!) summarize and amend the article? 69.154.23.143

Ok, I suck at this editing stuff... But I am a medical student and have done research into clenbuterol and other doping agents. First, cardiac myopathy does not mean thickening of heart muscle specifically, it means diseased heart muscle. The disease can be one of many, as you will see if you search for cardiomyopathy here on Wiki or anywhere else. There is actually evidence in animal models that beta2-receptor agonists (such as clenbuterol) has a stimulatory effect on the healing of cardiac myopathys caused by ischemia ^[1] (loss of blood supply to heart wall, as in a heart attack).

Second, of course the use of clenbuterol can be dangerous... if it's not used correctly. That means keeping the right dosage, and timing of doses. Clenbuterol has a very long half-life, which means it will stay in the body for a long time before beeing excreted or metabolized. This in turn means that doses can't be taken to close to each other, or overdosing may occur. Now, overdosing clenbuterol is very bad indeed. I read in a thread downstream from this one someone asking if he should take 20 mg of clenbuterol. I seriously hope he meant 20 mcg, since 20 mg may very well have killed him. Overdosing is the greatest risk associated with clenbuterol use, since overdosing causes tachychardia and hypokalemia (^[2](extremely fast heartbeats and dangerously low levels of potassium) which among people with an underlying disease can lead to heart attacks or strokes. —Preceding unsigned comment added by Dr Mixe (talk • contribs) 00:46, 24 January 2009 (UTC)[reply]

Neutrality?

I challenged the neutrality of the first sentence that says Clenbuterol is not a steroid but is thought of as one due to its 'abuse' in bodybuilding. Who, exactly, is it that thinks of Clenbuterol as a steroid? It's a bronchodialator that is used in bodybuilding for it's thermogenic properties to increase metabolism and shed fat before a subjective modeling contest. And who defines the word 'abuse'? If someone safely and effectively uses this drug to lose fat, do you define that as abuse? Many drugs that were developed and sent to market for purpose A were later found to work perfectly for purpose B. Look up Buproprion HCL.

As for the above posted question; Clenbuterol was originally developed for human consumption. However, when Salbutamol was developed it was a better drug for the purpose of bronchodialation. It could be delivered in an atomized form and it had a much much shorter half life than its chemical cousin, Clenbuterol (1.6 hours vs. 36 hours). I posted a link at the bottom of the Clenbuterol page that shows the doses at which athletes safely use clenbuterol to burn fat. BPBomber 16:12, 16 January 2007 (UTC)[reply]

The current page is somewhat contradictory. On the one hand, clenbuterol is used to reduce weight in humans, on the other hand, it is used to increase weight in animals. Can someone resolve this, please?

-- it's used to burn fat, not reduce weight. —Preceding unsigned comment added by 204.193.129.239 (talk) 23:47, 6 December 2007 (UTC)[reply]

Yes, it is used as a bronchodilator and as a thermogenic agent to burn fat and raise metabolism just like Ephedrine based diet pills. —Preceding unsigned comment added by 64.131.233.109 (talk) 21:05, 12 July 2008 (UTC)[reply]

I looked on the official websites at NIH and the Mayo Clinic and did not find anything on the Mayo Clinic website. There must be a blip on the NIH website, but I could not find it. This drug is a bronchodilator. It has the appearance (not literal) of epinephrine and will raise the blood pressure. If you lose any amount of weight without the drug, you will lose fat (unless your body has NO fat). If it is like ephedrine, then it resembles caffeine and will increase the heart rate. I cannot find anything ( no reference) scientific about this drug. Someone needs to do some serious research about this, write about it and provide current references. Warren

dosage

How often do you take a 20 mg dosage? Do you take with water? In the morning? ect. I ordered some on line and the instruction came in a different language!!!

This is not a discussion forum for clenbuterol dosage.GetAnabolics 20:09, 12 March 2007 (UTC)[reply]

Clenbuterol

I believe this sentence is not accurate: Clenbuterol is often mistaken for a steroid because of its illicit use in athletics. I suggest the following modification: ...often mistaken for an anabolic androgenic steroid....GetAnabolics 20:09, 12 March 2007 (UTC)[reply]

please please tell me you didn't take 20 mg? You meant 20 mcg, right? Cause otherwise you're dead. It's all in the numbers. Micrograms should never be confused with milligrams. —Preceding unsigned comment added by Dr Mixe (talk • contribs) 00:51, 24 January 2009 (UTC)[reply]

Recreational use

What about recreational use? I've heard it's taken by junkies... --Alexander Ivashkin 19:55, 23 May 2007 (UTC) The entry does not address whether it is legal to have or not, just weasel words about it not being approved.[reply]

Fair use rationale for Image:Clenbuterol.png

Image:Clenbuterol.png is being used on this article. I notice the image page specifies that the image is being used under fair use but there is no explanation or rationale as to why its use in this Wikipedia article constitutes fair use. In addition to the boilerplate fair use template, you must also write out on the image description page a specific explanation or rationale for why using this image in each article is consistent with fair use.

Please go to the image description page and edit it to include a fair use rationale. Using one of the templates at Wikipedia:Fair use rationale guideline is an easy way to insure that your image is in compliance with Wikipedia policy, but remember that you must complete the template. Do not simply insert a blank template on an image page.

If there is other fair use media, consider checking that you have specified the fair use rationale on the other images used on this page. Note that any fair use images lacking such an explanation can be deleted one week after being tagged, as described on criteria for speedy deletion. If you have any questions please ask them at the Media copyright questions page. Thank you.

BetacommandBot (talk) 20:33, 13 February 2008 (UTC)[reply]

Contradiction

In the Effects and Dosage section it says this:

It increases the rate at which fats are metabolized, simultaneously increasing the body's BMR.

Human Use:

It is commonly used as a slimming aid despite lack of sufficient clinical evidence supporting such use[2].

If it increases the basal metabolic rate then it surely must work as a slimming aid? 78.82.141.241 (talk) 18:30, 25 March 2010 (UTC)[reply]

This section has one reference and it is a blog. I didn't see anything about the drug in it. I may have missed it or it is from a long ago date. The rest of the paragraph has no reference whatsoever. I do not see any medical or scientific reference at all for this drug. There needs to be more 'accurate' information about it and some reasonable references for it. Warren —Preceding unsigned comment added by 71.140.91.198 (talk) 05:16, 30 September 2010 (UTC)[reply]

Alberto Contador

I wonder if this page is the right place to discuss current doping allegations on Alberto Contador. —Preceding unsigned comment added by Juancdelalamo (talk • contribs) 00:49, 30 September 2010 (UTC)[reply]

Not sure if it is, but reporting his defenses as widely-accepted fact, and then citing to his press report, violates rules of neutrality. I've edited, but feel free to delete the whole reference. —Preceding unsigned comment added by 96.241.14.32 (talk) 01:45, 30 September 2010 (UTC)[reply]

^ J Pharmacol Exp Ther. 2006 May;317(2):553-61. Epub 2006 Jan 18
^ J Med Toxicol. 2007 Jun;3(2):56-60.Click here to read

[1] J Pharmacol Exp Ther. 2006 May;317(2):553-61. Epub 2006 Jan 18

[2] J Med Toxicol. 2007 Jun;3(2):56-60.Click here to read

[1]

[2]