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This is an old revision of this page, as edited by 75.139.32.32 (talk) at 02:25, 3 February 2012. The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Dietary sources

The article cites a biased, non-scientific reference "Dietary Guidlines for Americans 2005", USDA, for the following claim: "Those wishing to reduce their cholesterol through a change in diet should aim to consume less than 7% of their daily calories from animal fat and fewer than 200 mg of cholesterol per day."

The claim should either be substantiated by a peer reviewed scientific study or removed. — Preceding unsigned comment added by Xkit (talk • contribs) 06:02, 17 April 2011 (UTC)[reply]

Conflicting sentences: A change in diet in addition to other lifestyle modifications may help reduce blood cholesterol. It is debatable that a diet, changed to reduce dietary fat and cholesterol, can lower blood cholesterol levels... — Preceding unsigned comment added by Scottbeckford (talk • contribs) 19:08, 19 November 2011 (UTC)[reply]

I've just made some edits. The USDA's advice is now presented as a guideline coming from the USDA. Also "animal fat" was inserted by a vandal - it originally had "saturated fat".. The conflict and the latter half of the section have also been cleared up. eug (talk) 13:32, 14 December 2011 (UTC)[reply]

Membrane fluidity

Under the section discussing biological functions, cholesterol is said to decrease membrane fluidity. While the source regarding this is from 2011, the actual information it is based off of may not be. According to the 2008 version of the Molecular Biology of the Cell:

"Cholesterol modulates the properties of lipid bilayers. When mixed with phospholipids, it enhances the permeability-barrier properties of the lipid bilayer. It inserts into the bilayer with its hydroxyl group close to the polar head groups of the phospholipids, so that its rigid, platelike steroid rings interact with-and partly immobilize-those regions of the hydrocarbon chains closest to the polar head groups (see Figure 10-5). By decreasing the mobility of the first few CH2 groups of the hydrocarbon chains of the phospholipid molecules, cholesterol makes the lipid bilayer less deformable in this region and thereby decreases the permeability of the bilayer to small water-soluble molecules. Although cholesterol tightens the packing of the lipids in a bilayer, it does not make membranes any less fluid. At the high concentrations found in most eucaryotic plasma membranes, cholesterol also prevents the hydrocarbon chains from coming together and crystallizing."

If you check earlier versions, it also mentions the fluidity-reducing properties of cholesterol so I suspect this is a change that is slowly being accepted. Does anyone have any input on this? — Preceding unsigned comment added by Serafap (talk • contribs) 16:39, 6 December 2011 (UTC)[reply]

Schizophrenic advice on diet effects

In one section, it's stated that diet has been shown to not affect cholesterol levels. In another, it states that a vegetarian or low protein diet improves levels. I suspect multiple editing hands with people adding in what they felt was right. I have no problem with multiple viewpoints backed up by citations, but right now, it sounds like we're contradicting ourselves. -74.200.4.237 (talk) 18:13, 6 December 2011 (UTC)[reply]

Problem converting to PDF

When this article is converted to PDF, blank pages are generated, pages 9 & 10 Repagers (talk) 01:35, 27 January 2012 (UTC)[reply]

Ancel Keys

Shaddix (talk · contribs), using IPs, has been repeatedly adding URLs to references from 1952 and 1954 from Ancel Keys. Repeated requests for discussion have not lead to anything. Whether orally ingested cholesterol leads to hypercholesterolaemia is an interesting discussion, but I would not want to introduce content with such ancient references. I requested for the article to be semi-protected, but full protection has resulted instead. JFW | T@lk 20:54, 1 February 2012 (UTC)[reply]

Here's a quote from the CURRENT article: " The body compensates for cholesterol intake by reducing the amount synthesized.[citation needed]". So you're saying wikipedia is better off having statements with no source whatsoever, rather than ones from the 1950s? Introducing content? what content have I introduced? The content is already there, I'm only providing the source. I provided another source from I think it was the 1990s. The only reason I was editing from other IP addresses is because I was posting from my phone and didn't feel like logging in. Shaddix (talk) 13:03, 2 February 2012 (UTC)[reply]

PMID 16340654 is vaguely useful in the sense that it is a secondary source, but the sources are still not remotely the kind that is actually useful. It would be very helpful if you could at least make an effort to format your sources, because bare URLs are not suitable. JFW | T@lk 00:01, 3 February 2012 (UTC)[reply]

If you don't want me to do it that way then change the http://en.wikipedia.org/wiki/Wikipedia:Citation_needed page to say "do not provide a source unless you can properly format it". Riddle me this. You do state that a statement of fact with no source on wikipedia is superior to a statement with a source. True or false? Your actions so far have pointed to true. I guess I should just go remove any sources you've provided and replace them with citation needed. I would be doing you a favor in that case. 75.139.32.32 (talk) 02:25, 3 February 2012 (UTC)[reply]

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