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Thymopentin

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Thymopentin
Clinical data
Other names(3S)-3-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-hydroxy-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
ATC code
Identifiers
  • L-arginyl-L-lysyl-L-α-aspartyl-L-valyl-L-tyrosine
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
NIAID ChemDB
CompTox Dashboard (EPA)
ECHA InfoCard100.242.320 Edit this at Wikidata
Chemical and physical data
FormulaC30H49N9O9
Molar mass679.76496 g/mol g·mol−1
3D model (JSmol)
  • O=C(N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)Cc1ccc(O)cc1)C(C)C)CC(=O)O)CCCCN)[C@@H](N)CCC/N=C(\N)N
  • InChI=1S/C30H49N9O9/c1-16(2)24(28(46)38-22(29(47)48)14-17-8-10-18(40)11-9-17)39-27(45)21(15-23(41)42)37-26(44)20(7-3-4-12-31)36-25(43)19(32)6-5-13-35-30(33)34/h8-11,16,19-22,24,40H,3-7,12-15,31-32H2,1-2H3,(H,36,43)(H,37,44)(H,38,46)(H,39,45)(H,41,42)(H,47,48)(H4,33,34,35)/t19-,20-,21-,22-,24-/m0/s1 checkY
  • Key:PSWFFKRAVBDQEG-YGQNSOCVSA-N checkY
  (verify)

Thymopentin is an immunostimulant.

It interacts with T cells.[1]

It is a thymic polypeptide.[2]

It is a thymic polypeptide.[2]

References

  1. ^ Liu Z, Zheng X, Wang J, Wang E (2007). Egli, Martin (ed.). "Molecular analysis of thymopentin binding to HLA-DR molecules". PLoS ONE. 2 (12): e1348. doi:10.1371/journal.pone.0001348. PMC 2137936. PMID 18159232.{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)
  2. ^ a b Peng Y, Chen Z, Yu W; et al. (2008). "Effects of thymic polypeptides on the thymopoiesis of mouse embryonic stem cells". Cell biology international. 32 (10): 1265–71. doi:10.1016/j.cellbi.2008.07.011. PMID 18692582. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link) Cite error: The named reference "pmid18692582" was defined multiple times with different content (see the help page).