Metanx
| Combination of | |
|---|---|
| L-methylfolate | vitamin |
| Pyridoxal 5'-phosphate | vitamin |
| Methylcobalamin | vitamin |
| Clinical data | |
| AHFS/Drugs.com | Monograph |
| Identifiers | |
| ChemSpider | |
  (what is this?) (verify) | |
Metanx is a medical food made by Pamlab that contains L-methylfolate (vitamin B9), methylcobalamin (vitamin B12) and pyridoxal 5'-phosphate (vitamin B6). It is a vitamin B supplement.
It is indicated for the treatment of endothelial dysfunction and hyperhomocysteinemia. In particular it has been shown to be an effective treatment for diabetic peripheral neuropathy[1][2], reducing symptoms of neuropathy, though not improving sensation.[3] It can also improve lower extremity ulcerations such as diabetic foot ulcers.[4]
Metanx contains the following active ingredients (per capsule):
- L-methylfolate (Metafolin): 3 mg
- Pyridoxal 5'-phosphate: 35 mg
- Methylcobalamin: 2 mg
References
- ^ Vascular Disease Management. 2 (Suppl 6): 1S–9S. 2005.
{{cite journal}}: Missing or empty|title=(help) - ^ Yaqub, Basim A; et al. (1992). "Effects of methylcobalamin on diabetic neuropathy". Clinical Neurology and Neurosurgery. 94: 105–111.
{{cite journal}}: Explicit use of et al. in:|author=(help) - ^ Fonseca, Vivian (2013). "Metanx in type 2 diabetes with peripheral neuropathy: a randomized trial". The American journal of medicine. 126 (2): 141–149. doi:10.1016/j.amjmed.2012.06.022. PMID 23218892.
{{cite journal}}:|access-date=requires|url=(help) - ^ Boykin JV, Baylis C (2006). "Homocysteine--A Stealth Mediator of Impaired Wound Healing: A Preliminary Study". Wounds. 18 (4): 101–116.
External links
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