Spleen transplantation

Spleen transplantation
Spleen transplantation
ICD-9-CM	41.94
	[edit on Wikidata]

Spleen transplantation is the transfer of spleen or spleen fragments from one individual to another. It is under research for induction of immunological tolerance for other transplanted organs. Success has been achieved in rodent models. Recently, evidence has been obtained for a tolerogenic effect of a spleen transplant in miniature swine (Frank JMF Dor, PhD thesis). Also, the spleen harbors primitive hematopoietic progenitor cells. Spleen transplantation surgery has been performed on humans with mixed results.^[1]^[2]

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^ Wu; et al. (January 2011). "Graft-versus-host disease after intestinal and multivisceral transplantation". Transplantation. 91 (2): 219–224. PMID 21076376. {{cite journal}}: Explicit use of et al. in: |last1= (help)
^ Deierhoi; et al. (April 1986). "Lethal graft-versus-host disease in a recipient of a pancreas-spleen transplant". Transplantation. 41 (4): 544–546. PMID 3515658. {{cite journal}}: Explicit use of et al. in: |last1= (help)

[Wu-1] Wu; et al. (January 2011). "Graft-versus-host disease after intestinal and multivisceral transplantation". Transplantation. 91 (2): 219–224. PMID 21076376. {{cite journal}}: Explicit use of et al. in: |last1= (help)

[Deierhoi-2] Deierhoi; et al. (April 1986). "Lethal graft-versus-host disease in a recipient of a pancreas-spleen transplant". Transplantation. 41 (4): 544–546. PMID 3515658. {{cite journal}}: Explicit use of et al. in: |last1= (help)

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v t e Procedures relating to the haematopoetic and lymphatic systems
Bone marrow	Stem cell transplantation Hematopoietic stem cell transplantation
Thymus	Removal Transplantation
Spleen	Removal Transplantation
Lymph nodes	Lymphadenectomy Neck dissection Retroperitoneal lymph node dissection Lymph node biopsy
Tonsils	see Template:Procedures on the mouth and pharynx
Imaging	Lymphogram