Methoxypropane: Difference between revisions
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Updating {{chembox}} (changes to watched fields - updated 'UNII_Ref', 'ChEMBL_Ref', 'KEGG_Ref') per Chem/Drugbox validation (report errors or [[user talk: |
m GHS update: remove empty EUClass/Rphrase/Sphrase parameters (depr), replaced: | EUClass = | → | (3), | SPhrases = | → | |
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{{Chembox |
{{Chembox |
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| Watchedfields = changed |
| Watchedfields = changed |
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| verifiedrevid = |
| verifiedrevid = 431188616 |
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| ImageFile=methoxypropane.svg |
| ImageFile = methoxypropane.svg |
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| PIN = 1-Methoxypropane |
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| OtherNames=Propane, 1-methoxy-<br />methyl propyl ether<br />Metopryl<br />Neothyl<br />propane, 1-methoxy<br />methyl n-propyl ether |
| OtherNames = Propane, 1-methoxy-<br />methyl propyl ether<br />Metopryl<br />Neothyl<br />propane, 1-methoxy<br />methyl n-propyl ether |
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|Section1={{Chembox Identifiers |
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| Abbreviations= |
| Abbreviations = |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 10709 |
| ChemSpiderID = 10709 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = VNKYTQGIUYNRMY-UHFFFAOYSA-N |
| StdInChIKey = VNKYTQGIUYNRMY-UHFFFAOYSA-N |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| CASNo=557-17-5| |
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| CASNo = 557-17-5 |
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EINECS=209-158-7| |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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PubChem=11182| |
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| UNII = 37D15RN2Z8 |
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SMILES = O(CCC)C |
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| EINECS = 209-158-7 |
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| UNNumber = 2612 |
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InChI=1/C4H10O/c1-3-4-5-2/h3-4H2,1-2H3}}| |
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| PubChem = 11182 |
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Section2={{Chembox Properties |
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| SMILES = O(CCC)C |
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| Formula=C<sub>4</sub>H<sub>10</sub>O |
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| InChI = 1/C4H10O/c1-3-4-5-2/h3-4H2,1-2H3 |
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| MolarMass=74.12 |
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| RTECS = KO2280000 |
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| Density=0.7356 g/cm<sup>3</sup> |
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}} |
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| Solubility= |
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|Section2={{Chembox Properties |
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| MeltingPt= |
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| Formula = C<sub>4</sub>H<sub>10</sub>O |
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| BoilingPtC=38.8 |
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| MolarMass = 74.12 |
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| pKa= |
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| Density = 0.7356 g/cm<sup>3</sup> |
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| pKb=| |
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| MeltingPtC = |
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IsoelectricPt=| |
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| BoilingPtC = 38.8 |
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DeltaHf=| |
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| pKa = |
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DeltaHc=| |
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| pKb = |
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Solubility=30.5 g/L| |
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| IsoelectricPt = |
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SolubleOther=| |
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| Solubility = 30.5 g/L |
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Solvent=| |
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| SolubleOther = |
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MeltingPt=| |
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| Solvent = |
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BoilingPt=| |
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| SpecRotation = |
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| RefractIndex = 1.35837 (14.3 °C) |
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| Viscosity = 0.3064 cP (0.3 °C) |
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| Dipole = |
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}} |
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|Section3={{Chembox Structure |
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| CrystalStruct = |
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| Coordination = |
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| MolShape = |
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| Dipole = |
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}} |
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|Section4={{Chembox Thermochemistry |
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| DeltaHf = |
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| DeltaHc = |
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| Entropy = |
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| HeatCapacity = |
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}} |
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Section5={{Chembox Pharmacology| |
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|Section5={{Chembox Pharmacology |
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ATCCode=| |
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| Bioavail = |
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DrugBank=| |
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| Metabolism = |
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Bioavail=| |
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| HalfLife = |
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Metabolism=| |
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| Excretion = |
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HalfLife=| |
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| Pregnancy_category = |
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Excretion=| |
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| AdminRoutes = inhalation |
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PregCat=| |
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}} |
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AdminRoutes=inhalation}}| |
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|Section6={{Chembox Explosive |
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| ShockSens = |
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| FrictionSens = |
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| DetonationV = |
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ExplosiveV=| |
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| REFactor = |
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}} |
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Section7={{Chembox Hazards| |
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|Section7={{Chembox Hazards |
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EUClass=| |
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| MainHazards = |
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| NFPA-H=0 |
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| NFPA-F=3 |
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| NFPA-R=0 |
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| NFPA-S = |
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| FlashPt= < |
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RPhrases=| |
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| FlashPtC = -20 |
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SPhrases=| |
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| AutoignitionPt = |
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RSPhrases=| |
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| ExploLimits = 1.9-11.8 |
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FlashPt=< -20 °C| |
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| PEL = |
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Autoignition=| |
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}} |
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ExploLimits=1.9-11.8| |
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|Section9={{Chembox Related |
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PEL=| |
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| OtherAnions = |
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RTECS= KO2280000}}| |
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| OtherCations = |
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Section8={{Chembox Supplement}}| |
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| OtherFunction = |
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Section9={{Chembox Related| |
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| OtherFunction_label = |
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OtherAnions=| |
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| OtherCompounds = |
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OtherCations=| |
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}} |
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OtherFunctn=| |
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Function=| |
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OtherCpds=}} |
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}} |
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'''Methoxypropane''', or '''methyl propyl ether''', is an [[ether]] once used as a [[general anaesthetic]].<ref>White, Mary Louise T.; Shane, Sylvan M.; Krantz, John C., Jr. "Anesthesia. XXI. Propyl methyl ether as an inhalation anesthetic in man", ''Anesthesiology'', (1946), 7, 663-7.</ref> It is a clear colorless flammable liquid with a boiling point of 38.8 °C.<ref>''Merck Index'', 11th edition, '''6031'''.</ref> |
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Marketed under the trade names '''Metopryl''' and '''Neothyl''', methoxypropane was used as an alternative to [[diethyl ether]] because of its greater potency. Its use as an anaesthetic has since been supplanted by modern [[halogenated ether]]s which are much less flammable. |
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'''Methoxypropane''', or '''methyl propyl ether''', is an [[ether]] once used as a [[general anaesthetic]].<ref>White, Mary Louise T.; Shane, Sylvan M.; Krantz, John C., Jr. "Anesthesia. XXI. Propyl methyl ether as an inhalation anesthetic in man", ''Anesthesiology'', (1946), 7, 663-7.</ref> It is a clear colorless flammable liquid with a boiling point of 38.8 °C.<ref>''Merck Index'', 11th edition, '''6031'''.</ref> |
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Marketed under the trade names Metopryl and Neothyl, methoxypropane was used as an alternative to [[diethyl ether]] because of its greater potency. Its use as an anaesthetic has since been supplanted by modern [[halogenated ether]]s which are much less flammable. |
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==References== |
==References== |
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{{General anesthetics}} |
{{General anesthetics}} |
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{{GABAAR PAMs}} |
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[[Category: |
[[Category:Dialkyl ethers]] |
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[[Category:General anesthetics]] |
[[Category:General anesthetics]] |
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[[Category:GABAA receptor positive allosteric modulators]] |
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{{nervous-system-drug-stub}} |
{{nervous-system-drug-stub}} |
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{{organic-compound-stub}} |
{{organic-compound-stub}} |
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[[de:Methylpropylether]] |
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[[el:Μεθυλοπροπυλαιθέρας]] |
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[[fr:Méthoxypropane]] |
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[[ja:メチルプロピルエーテル]] |
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[[pt:Metoxipropano]] |