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- AlkB (Alkylation B) is a protein found in E. coli, induced during an adaptive response and involved in the direct reversal of alkylation damage. AlkB...12 KB (1,337 words) - 16:19, 4 January 2024
- Alpha-ketoglutarate-dependent hydroxylases (category Enzymes)many biosynthetic and metabolic pathways; for example, in E. coli, the AlkB enzyme is associated with the repair of damaged DNA. In plants, αKG-dependent...36 KB (3,976 words) - 06:03, 27 May 2024
- 2OG-Fe(II) dioxygenase, along with DNA repair protein AlkB, and disease resistant EGL-9. The enzyme was found to be a type of hydroxylases used in the substrate...5 KB (628 words) - 16:32, 4 October 2024
- Alkane 1-monooxygenase (category Heme enzymes)1-hydroxylase, AlkB, and alkane hydroxylase. It contains a diiron non-heme active site. Recently two crystal structures of the enzyme have appeared that...4 KB (405 words) - 06:26, 6 September 2023
- Begley U, Paules RS, Dedon PC, Begley TJ, Samson LD (May 2010). "Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification...2 KB (252 words) - 16:06, 26 August 2023
encoding protein AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase AMOTL1: angiomotin-like protein 1 AMPD3: encoding enzyme AMP deaminase 3 API5:...28 KB (1,930 words) - 22:58, 28 March 2024- Adaptive response (section alkB)Weber PC, Gibney BR, Hunt JF. (2006). Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB. Nature 439(7078):879-84....10 KB (1,175 words) - 21:30, 2 June 2024
- DNA-(apurinic or apyrimidinic site) lyase (category Enzymes of known structure)5'-product adduct is generated following AP lyase activity of human ALKBH1 (AlkB homologue 1)". Biochem J. 452 (3): 509–18. doi:10.1042/BJ20121908. PMC 4126167...16 KB (1,723 words) - 04:39, 23 September 2024
- mutagenic. The Ada response includes the expression of four genes: ada, alkA, alkB, and aidB. The product of ada gene, the Ada protein, is an activator of transcription...10 KB (1,387 words) - 13:30, 5 April 2023
- enzymes are two factors that act to accomplish this remodeling process after DNA damage occurs. Further DNA repair steps, involving multiple enzymes,...81 KB (10,099 words) - 11:45, 3 September 2024
- ABH1, alkB (gene)) is an enzyme with systematic name methyl DNA-base, 2-oxoglutarate:oxygen oxidoreductase (formaldehyde-forming). This enzyme catalyses...2 KB (204 words) - 06:08, 15 November 2023
two known PCNA-interacting motifs PCNA-interacting peptide (PIP) box and AlkB homologue 2 PCNA interacting motif (APIM). Proteins binding to PCNA via the...53 KB (6,158 words) - 18:54, 23 April 2024
dioxygenase FTO is an enzyme that in humans is encoded by the FTO gene located on chromosome 16. As one homolog in the AlkB family proteins, it is the...35 KB (3,886 words) - 21:41, 7 June 2024
Dioxygenase (section Iron-containing enzymes)Dioxygenases are oxidoreductase enzymes. Aerobic life, from simple single-celled bacteria species to complex eukaryotic organisms, has evolved to depend...24 KB (2,879 words) - 00:45, 22 June 2024- and quantitation by deep sequencing, which can be overcome by enzyme (such as PNK and AlkB) pre-treatment. Depending on the purpose of the analysis, RNA-seq...14 KB (2,056 words) - 14:29, 30 April 2022
revitalized the interests in the study of m6A. A second m6A demethylase alkB homolog 5 (ALKBH5) was later discovered as well. The biological functions...53 KB (5,629 words) - 21:25, 24 September 2024
