Chromosome 11 (human)

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Chromosome 11 (human)
Human male karyotpe high resolution - Chromosome 11 cropped.png
Pair of human chromosome 11 (after G-banding).
One is from mother, one is from father.
Human male karyotpe high resolution - Chromosome 11.png
Chromosome 11 pair in human male karyogram.
Length (bp) 135,086,622 bp[1]
No. of genes 2,920[2]
Type Autosome
Centromere position Submetacentric[4]
RefSeq NC_000011
GenBank CM000673
Map of Chromosome 11
Ideogram. For band names, see locus.

Chromosome 11 is one of the 23 pairs of chromosomes in humans. Humans normally have two copies of this chromosome. Chromosome 11 spans about 135 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies. In January 2017, two estimates differed insignificantly (0.3%), with one estimate giving 2,920[2] genes, and the other estimate giving 2,893[3] genes.

At 21.5 genes per megabase, Chromosome 11 is one of the most gene-rich, and disease-rich, chromosomes in the human genome.

More than 40% of the 856 olfactory receptor genes in the human genome are located in 28 single-gene, and multi-gene, clusters along this chromosome.


The following are some of the genes located on chromosome 11:

Diseases and disorders[edit]

The following diseases and disorders are some of those related to genes on chromosome 11:


  1. ^ "Human Genome Assembly GRCh38.p10 - Genome Reference Consortium". National Center for Biotechnology Information. 2017-01-06. Retrieved 2017-03-04. 
  2. ^ a b "Homo sapiens (human) Chromosome 16". NCBI Map Viewer. National Center for Biotechnology Information. Retrieved January 20, 2017. 
  3. ^ a b "Homo sapiens: Chromosome summary: Chromosome 11:1-135086622". Wellcome Trust Sanger Institute. Vega Genome Browser 58. Retrieved January 20, 2017. 
  4. ^ "Table 2.3: Human chromosome groups". Human Molecular Genetics (2nd ed.). Garland Science. 1999. 
  5. ^ INS - insulin - Genetics Home Reference
  6. ^ "Autism gene breakthrough hailed". Health. BBC NEWS. 2007-02-19. Retrieved 2010-01-02. 
  7. ^ Human Genome Project Information Site Has Been Updated