GSDMB: Difference between revisions
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{{Short description|Protein-coding gene in the species Homo sapiens}} |
{{Short description|Protein-coding gene in the species Homo sapiens}} |
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{{Infobox_gene}} |
{{Infobox_gene}} |
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Latest revision as of 08:52, 28 April 2024
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | GSDMB, GSDML, PRO2521, PP4052, gasdermin B, GSDMB-1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 611221 HomoloGene: 88856 GeneCards: GSDMB | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Gasdermin B is a protein that in humans is encoded by the GSDMB gene. [3]
Function[edit]
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.
References[edit]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000073605 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Gasdermin B". Retrieved 2016-08-26.
Further reading[edit]
- Katoh M, Katoh M (2004). "Evolutionary recombination hotspot around GSDML-GSDM locus is closely linked to the oncogenomic recombination hotspot around the PPP1R1B-ERBB2-GRB7 amplicon". Int. J. Oncol. 24 (4): 757–63. doi:10.3892/ijo.24.4.757. PMID 15010812.
 | This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it. |
This article incorporates text from the United States National Library of Medicine, which is in the public domain.