Talk:Clonidine

I've been on a lot of medications used to treat my anxiety. The only drug that seemed to help me was Lorazapan, but over time it doesnt have nearly the same effect compared to when I first used it. Clonidine, however, has helped me and many others that are having high anxiety type issues. I just think this page needs a touch about how it can help anxiety, and also the long term effects of this specific medication. —Preceding unsigned comment added by 66.30.235.251 (talk) 06:19, 13 September 2007 (UTC)

Contrary to the article as written, I do not think Clonidine is generally used to "treat" ADHD, although many ADHD children receive it, off label at bedtime, to induce sleep. I suspect same is true with Tourette's although I am less certain of that. Although I am not qualified to prescribe, I deal with many children with both diagnoses and I only see it prescribed for use at bedtime. It is a sleep medication of choice because it does not have addictive potential and it does get the kids to slow down physically at bedtime. But I do not think any clinician would want children taking it because of ADHD during the active part of their day. Also note that clonidine and Klonopin are BOTH used to induce sleep (although not likely at the same time for the same person).

I looked at the study cited where the citation suggests otherwise. However that is not what the actual article says. It refers to a test of Ritalin and Clonidine used in combination. While I have not encountered this with children I have worked with (unless the Clonidine was administered only at bedtime) the COMBINATION makes sense. But I still doubt that Clonidine, by itself, is an appropriate treatment for either disorder. 70.90.220.214 22:04, 27 March 2007 (UTC)

There is a lot of info on this page[[1]] --Clawed 05:07, 16 Jul 2004 (UTC)

Unless I got the wrong drug, Clonidine is also used off-label to treat insomnia. I once took it when I was young in really small doses. --User:Arm

You're probably thinking of clonazepam (Klonopin). - Nunh-huh 05:43, 3 Mar 2005 (UTC)

I was recently (yesterday) perscribed Clonidine by my psychiatrist for dealing with panic attacks and additionally to help with insomnia -- Anonymous 19:44, 3 February 2006 (UTC)

clonidine can be used for ADHD treatment and tics treatment in children(Dr Hussein Abdeldayem , Alex, Egypt)

I was prescribed clonidine specifically for my mild Tourette's syndrome, and it works very well. VCUchem 03:28, 10 April 2007 (UTC)

My son, 4.5 years old, has been on clonidine for two week to treat ADD, his prescription is 0.05mg. It is working well, but worried about longterm negative effects. Any articles? (user:woodmac)(December 18 2008)

Clonidine Transdermal "patch" .3 Is currently being used to treat my daughter's Cycling Vomiting Syndrome. see ref: http://digestive.niddk.nih.gov/ddiseases/pubs/cvs/#6 —Preceding unsigned comment added by Morrisindustries (talk • contribs) 12:11, 15 January 2008 (UTC)

Quitting smoking

The Surgeon General suggests that Clonidine can be used to aid in quitting smoking after nicotine replacement methods have failed. A potential source is http://surgeongeneral.gov/tobacco/treating_tobacco_use.pdf

Side-effects?

Did anyone ever hear of very bad chest and back pain with this medicine? Taking it four times a day, and my upper back and chest is killing me

Your side effect was probably a rare reaction. The only side effect I experienced was being extremely tired at first.

The most popular understated side effect of this medication is, for lack any milder way to put it, catastrophic loss of consciousness. Not so much "put them out like a light", but more like drop them like a punch from Mike Tyson, where they stand.

VCUchem 03:24, 10 April 2007 (UTC)

Cleanup

This page is a candidate for cleanup. I propose that all of the benzodiazepines be wikified at once. The benzodiazepines are a significant family of drugs, and better information should be available here on Wikipedia, due to their widespread use.

Clonidine is not a benzodiazepine.

You must be thinking of Klonopin (clonazepam).

I agree that a lot of people do not understand that Klonopin is a completely different medication than clonadine!

Creditation

Clonidine is often used to treat tics, specifically Tourettes Disorder, due to research by Dr. Richard Ferre, M.D. of University of Utah. I do not have a link to the specific paper, but you can find it on a Google search "Richard Ferre"

Yea, i have Tourettes and i take this. EvilHom3r 18:49, 6 August 2007 (UTC)

I have used the patch form of this medicine before to treat parts/symptoms of Attention Deficit Hyperactivity Disorder, and it seems to work pretty well. User: mansharker8 —Preceding unsigned comment added by 207.157.138.39 (talk) 01:35, 30 October 2007 (UTC)

anyone use this to come off pain meds?

I have been on oxycontin for 2 years for severe arthritis pain. I am tired of narcotics so insisted my doctor get me off them at my last visit. She discourages my disuse but wrote me perscriptions for clonidine and atorax to help my detox symptons when I stop. Has anyone had any experience using this for that? Diannamo (talk) 00:41, 21 April 2008 (UTC)

Clean-Up (again?)

The muddle with clonazepam (Klonidine) here remains - for a start, one of the most common side effects of clonidine is insomnia (see the British National Formulary entry - probably same info listing in the Physicians Desk Ref too...) and I can hardly see it being rx'd for such. Indeed, its one of the drawbacks of using it for opiate withdrawal as the resultant insomnia can be severe and prolonged even after the acute symptons are over. In the UK, it is usually therefore prescribed for this purpose along with strong benzos such as Rohypnol or with benzo/chlorpromazine combinations to overcome this lack of efficacy. Anyway, someone ought to clear this up some more. If no-one better qualied tries, 'll come back and have a go. Plutonium27 (talk) 02:47, 5 June 2008 (UTC)

Adrenergic Agonist AND NE antagonist?

How is this drug a "α2 adrenergic agonist" AND "inhibits the release of norepinephrine (NE)". Can someone explain? —Preceding unsigned comment added by 144.126.53.164 (talk) 11:51, 20 October 2009 (UTC)

In response to "Adrenergic Agonist AND NE antagonist?" I was wondering the same thing, as I'm at work researching Clonidine. I found this on a website: "Clonidine is an agonist, an alpha-2 agonist to be precise. But it acts primarily on noradrenergic autoreceptors thereby decreasing norepinephrine release. Thus clonidine is a direct-acting a2-noradrenergic agonist with indirect-acting antagonist action at other noradrenergic targets. (It has the physiological/behavioral effect of an antagonist at most doses, but it's still technically an agonist!) " —Preceding unsigned comment added by 216.63.110.9 (talk) 07:33, 15 January 2010 (UTC)

Clonodine

Clonodine is not Klonopin (clonazepam), it is not a benzodiazepine like (Valium, diazepam, Xnanax, alprazolam, Ativan, lorazepam). etc... Clonidine is used alone or in combination with other medications to treat high blood pressure. Clonidine is in a class of medications called centrally acting alpha-agonist hypotensive agents. It works by decreasing your heart rate and relaxing the blood vessels so that blood can flow more easily through the body. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000623 —Preceding unsigned comment added by Jodiah (talk • contribs) 20:47, 29 June 2010 (UTC)

Structure

I'm no expert, but do the two structure models agree? The 3D model shows both N atoms of the imidazoline ring with H's (implying imidazolidine), whereas the planar model shows N at position 2 with no H (imizazoline). The 3D model shows the N of the amine with no H and the planar model shows it with one. —Preceding unsigned comment added by 220.244.145.200 (talk) 00:38, 8 December 2010 (UTC)

You are absolutely right. It is a mistake and should be corrected. The 3D model is missing one H atom.

Uses

There are two "Uses" paragraphs in the article. Should be restructured. — Preceding unsigned comment added by Vbond (talk • contribs) 06:25, 3 February 2011 (UTC)