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(+)-cubenene synthase

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(+)-cubenene synthase
Identifiers
EC no.4.2.3.63
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

(+)-Cubenene synthase (EC 4.2.3.63) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((+)-cubenene-forming).[1][2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (+)-cubenene + diphosphate

This enzyme requires presence of Mg2+.

References

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  1. ^ Nabeta K, Kigure K, Fujita M, Nagoya T, Ishikawa T, Okuyama H, Takasawa T (1995). "Bioynthesis of (+)-cubenene and (+)-epicubenol by cell-free extracts of cultured cells of Heteroscyphus planus and cyclization of [2H]farnesyl diphosphates". J. Chem. Soc., Perkin Trans. 1 (15): 1935–1939. doi:10.1039/P19950001935.
  2. ^ Nabeta K, Fujita M, Komuro K, Katayama K, Takasawa T (1997). "In vitro biosynthesis of cadinanes by cell-free extracts of cultured cells of Heteroscyphus planus". J. Chem. Soc., Perkin Trans. 1 (14): 2065–2070. doi:10.1039/A701145H.
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