List of EC numbers (EC 1)

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This list contains a list of EC numbers for the first group, EC 1, oxidoreductases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee.[1] The database is developed and maintained by Andrew McDonald.[2]

EC 1.1 Acting on the CH-OH group of donors[edit]

EC 1.1.1 With Nicotinamide adenine dinucleotide or NADP as acceptor[edit]

At present (October 2021) most of the entries from 343 onwards have no Wikipedia articles
  • EC 1.1.1.343: phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating)
  • EC 1.1.1.344: dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+]
  • EC 1.1.1.345: D-2-hydroxyacid dehydrogenase (NAD+)
  • EC 1.1.1.346: 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
  • EC 1.1.1.347: geraniol dehydrogenase (NAD+)|geraniol dehydrogenase (NAD+)
  • EC 1.1.1.348: (3R)-2′-hydroxyisoflavanone reductase
  • EC 1.1.1.349: norsolorinic acid ketoreductase
  • EC 1.1.1.350: ureidoglycolate dehydrogenase (NAD+)
  • EC 1.1.1.351: phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
  • EC 1.1.1.352: 5′-hydroxyaverantin dehydrogenase
  • EC 1.1.1.353: versiconal hemiacetal acetate reductase
  • EC 1.1.1.354: farnesol dehydrogenase (NAD+)
  • EC 1.1.1.355: 2′-dehydrokanamycin reductase
  • EC 1.1.1.356: GDP-L-colitose synthase
  • EC 1.1.1.357: 3α-hydroxysteroid 3-dehydrogenase
  • EC 1.1.1.358: 2-dehydropantolactone reductase
  • EC 1.1.1.359: aldose 1-dehydrogenase [NAD(P)+]
  • EC 1.1.1.360: glucose/galactose 1-dehydrogenase
  • EC 1.1.1.361: glucose-6-phosphate 3-dehydrogenase
  • EC 1.1.1.362: aklaviketone reductase
  • EC 1.1.1.363: glucose-6-phosphate dehydrogenase [NAD(P)+]
  • EC 1.1.1.364: dTDP-4-dehydro-6-deoxy-α-D-gulose 4-ketoreductase
  • EC 1.1.1.365: D-galacturonate reductase
  • EC 1.1.1.366: L-idonate 5-dehydrogenase (NAD+)
  • EC 1.1.1.367: UDP-2-acetamido-2,6-β-L-arabino-hexul-4-ose reductase
  • EC 1.1.1.368: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase
  • EC 1.1.1.369: D-chiro-inositol 1-dehydrogenase
  • EC 1.1.1.370: scyllo-inositol 2-dehydrogenase (NAD+)
  • EC 1.1.1.371: scyllo-inositol 2-dehydrogenase (NADP+)
  • EC 1.1.1.372: L-glyceraldehyde reductase
  • EC 1.1.1.373: sulfolactaldehyde 3-reductase
  • EC 1.1.1.374: UDP-N-acetylglucosamine 3-dehydrogenase
  • EC 1.1.1.375: L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
  • EC 1.1.1.376: L-arabinose 1-dehydrogenase [NAD(P)+]
  • EC 1.1.1.377: L-rhamnose 1-dehydrogenase (NADP+)
  • EC 1.1.1.378: L-rhamnose 1-dehydrogenase [NAD(P)+]
  • EC 1.1.1.379: (R)-mandelate dehydrogenase
  • EC 1.1.1.380: L-gulonate 5-dehydrogenase
  • EC 1.1.1.381: 3-hydroxy acid dehydrogenase
  • EC 1.1.1.382: ketol-acid reductoisomerase (NAD+)
  • EC 1.1.1.383: ketol-acid reductoisomerase [NAD(P)+]
  • EC 1.1.1.384: dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose 3-reductase
  • EC 1.1.1.385: dihydroanticapsin dehydrogenase
  • EC 1.1.1.386: ipsdienol dehydrogenase
  • EC 1.1.1.387: L-serine 3-dehydrogenase (NAD+)
  • EC 1.1.1.388: glucose-6-phosphate dehydrogenase (NAD+)
  • EC 1.1.1.389: 2-dehydro-3-deoxy-L-galactonate 5-dehydrogenase
  • EC 1.1.1.390: sulfoquinovose 1-dehydrogenase
  • EC 1.1.1.391: 3β-hydroxycholanate 3-dehydrogenase (NAD+)
  • EC 1.1.1.392: 3α-hydroxycholanate dehydrogenase (NADP+)
  • EC 1.1.1.393: 3β-hydroxycholanate 3-dehydrogenase (NADP+)
  • EC 1.1.1.394: aurachin B dehydrogenase
  • EC 1.1.1.395: 3α-hydroxy bile acid-CoA-ester 3-dehydrogenase
  • EC 1.1.1.396: bacteriochlorophyllide a dehydrogenase
  • EC 1.1.1.397: β-methylindole-3-pyruvate reductase
  • EC 1.1.1.398: 2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase
  • EC 1.1.1.399: 2-oxoglutarate reductase
  • EC 1.1.1.400: 2-methyl-1,2-propanediol dehydrogenase
  • EC 1.1.1.401: 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+)
  • EC 1.1.1.402: D-erythritol 1-phosphate dehydrogenase
  • EC 1.1.1.403: D-threitol dehydrogenase (NAD+)
  • EC 1.1.1.404: tetrachlorobenzoquinone reductase
  • EC 1.1.1.405: ribitol-5-phosphate 2-dehydrogenase (NADP+)
  • EC 1.1.1.406: galactitol 2-dehydrogenase (L-tagatose-forming)
  • EC 1.1.1.407: D-altritol 5-dehydrogenase
  • EC 1.1.1.408: 4-phospho-D-threonate 3-dehydrogenase
  • EC 1.1.1.409: 4-phospho-D-erythronate 3-dehydrogenase
  • EC 1.1.1.410: D-erythronate 2-dehydrogenase
  • EC 1.1.1.411: L-threonate 2-dehydrogenase
  • EC 1.1.1.412: 2-alkyl-3-oxoalkanoate reductase
  • EC 1.1.1.413: A-factor type γ-butyrolactone 1′-reductase (1S-forming)
  • EC 1.1.1.414: L-galactonate 5-dehydrogenase
  • EC 1.1.1.415: noscapine synthase
  • EC 1.1.1.416: isopyridoxal dehydrogenase (5-pyridoxolactone-forming)
  • EC 1.1.1.417: 3β-hydroxysteroid-4β-carboxylate 3-dehydrogenase (decarboxylating)
  • EC 1.1.1.418: plant 3β-hydroxysteroid-4α-carboxylate 3-dehydrogenase (decarboxylating)
  • EC 1.1.1.419: nepetalactol dehydrogenase
  • EC 1.1.1.420: D-apiose dehydrogenase
  • EC 1.1.1.421: D-apionate oxidoisomerase
  • EC 1.1.1.422: pseudoephedrine dehydrogenase
  • EC 1.1.1.423: (1R,2S)-ephedrine 1-dehydrogenase
  • EC 1.1.1.424: D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
  • EC 1.1.1.425: levoglucosan dehydrogenase
  • EC 1.1.1.426: UDP-N-acetyl-α-D-quinovosamine dehydrogenase

EC 1.1.2 With a cytochrome as acceptor[edit]

(*) No Wikipedia article

EC 1.1.3 With oxygen as acceptor[edit]

(*) No Wikipedia article

EC 1.1.4 With a disulfide as acceptor[edit]

  • EC 1.1.4.1: Now EC 1.17.4.4
  • EC 1.1.4.2: Now EC 1.17.4.5

EC 1.1.5 With a quinone or similar compound as acceptor[edit]

EC 1.1.9 With a copper protein as acceptor[edit]

EC 1.1.98 With other, known, acceptors[edit]

(*) No Wikipedia article

EC 1.1.99 With other acceptors[edit]

(*) No Wikipedia article

EC 1.2 Acting on the aldehyde or oxo group of donors[edit]

EC 1.2.1 With NAD or NADP as acceptor[edit]

EC 1.2.2 With a cytochrome as acceptor[edit]

EC 1.2.3 With oxygen as acceptor[edit]

EC 1.2.4 With a disulfide as acceptor[edit]


EC 1.2.5 With FAD as acceptor[edit]

EC 1.2.7 With an iron-sulfur protein as acceptor[edit]

EC 1.2.99 With other acceptors[edit]

EC 1.3 Acting on the CH-CH group of donors[edit]

EC 1.3.1 With NAD or NADP as acceptor[edit]

EC 1.3.2 With a cytochrome as acceptor[edit]

EC 1.3.3 With oxygen as acceptor[edit]

EC 1.3.5 With a quinone or related compound as acceptor[edit]

EC 1.3.7 With an iron-sulfur protein as acceptor[edit]

EC 1.3.8 With an FAD as prosthetic group[edit]

EC 1.3.98 With FMN acceptor[edit]

EC 1.3.99 With other acceptors[edit]

EC 1.4 Acting on the CH-NH2 group of donors[edit]

EC 1.4.1 With NAD or NADP as acceptor[edit]

EC 1.4.2 With a cytochrome as acceptor[edit]

EC 1.4.3 With oxygen as acceptor[edit]

EC 1.4.4 With a disulfide as acceptor[edit]

EC 1.4.5 With an iron-sulfur flavoprotein as acceptor[edit]

EC 1.4.7 With an iron-sulfur protein as acceptor[edit]

EC 1.4.9 With TTQ acceptors[edit]

EC 1.4.98 With tryptophan tryptophylquinone acceptors[edit]

EC 1.4.99 With other acceptors[edit]

EC 1.5 Acting on the CH-NH group of donors[edit]

EC 1.5.1 With NAD or NADP as acceptor[edit]

EC 1.5.3 With oxygen as acceptor[edit]

EC 1.5.4 With a disulfide as acceptor[edit]

EC 1.5.5 With a quinone or similar compound as acceptor[edit]

EC 1.5.7 With an iron-sulfur protein as acceptor[edit]

EC 1.5.8 With a flavin as acceptor[edit]

EC 1.5.99 With other acceptors[edit]

EC 1.6 Acting on NADH or NADPH[edit]

EC 1.6.1 With NAD or NADP as acceptor[edit]

EC 1.6.2 With a heme protein as acceptor[edit]

EC 1.6.3 With oxygen as acceptor[edit]

EC 1.6.4 With a disulfide as acceptor[edit]

EC 1.6.5 With a quinone or similar compound as acceptor[edit]

EC 1.6.6 With a nitrogenous group as acceptor[edit]

EC 1.6.7 With an iron-sulfur protein as acceptor[edit]

EC 1.6.8 With a flavin as acceptor[edit]

EC 1.6.99 With other acceptors[edit]

EC 1.7 Acting on other nitrogenous compounds as donors[edit]

EC 1.7.1 With NAD+ or NADP+ as acceptor[edit]

EC 1.7.2 With a cytochrome as acceptor[edit]

EC 1.7.3 With oxygen as acceptor[edit]

EC 1.7.5 With miscellaneous acceptors[edit]

EC 1.7.6 With hydrogen as acceptor[edit]

EC 1.7.7 With an iron-sulfur protein as acceptor[edit]

EC 1.7.99 With other acceptors[edit]

EC 1.8 Acting on a sulfur group of donors[edit]

EC 1.8.1 With NAD or NADP as acceptor[edit]

EC 1.8.2 With a cytochrome as acceptor[edit]

EC 1.8.3 With oxygen as acceptor[edit]

EC 1.8.4 With a disulfide as acceptor[edit]

EC 1.8.5 With a quinone or similar compound as acceptor[edit]

EC 1.8.6 With a nitrogenous group as acceptor[edit]

EC 1.8.7 With an iron-sulfur protein as acceptor[edit]

EC 1.8.98 With other, known, acceptors[edit]

EC 1.8.99 With other acceptors[edit]

EC 1.9 Acting on a heme group of donors[edit]

EC 1.9.3 With oxygen as acceptor[edit]

EC 1.9.6 With a nitrogenous group as acceptor[edit]

EC 1.9.99 With other acceptors[edit]

EC 1.10 Acting on diphenols and related substances as donors[edit]

EC 1.10.1 With NAD or NADP as acceptor[edit]

EC 1.10.2 With a cytochrome as acceptor[edit]

EC 1.10.3 With oxygen as acceptor[edit]

EC 1.10.99 With plastocyanin acceptors[edit]

EC 1.10.99 With other acceptors[edit]

EC 1.11 Acting on a peroxide as acceptor[edit]

EC 1.11.1 Peroxidases[edit]

EC 1.11.2 Peroxygenase[edit]

EC 1.12 Acting on hydrogen as donor[edit]

EC 1.12.1 With NAD or NADP as acceptor[edit]

EC 1.12.2 With a cytochrome as acceptor[edit]

EC 1.12.5 With a quinone or similar compound as acceptor[edit]

EC 1.12.7 With an iron-sulfur protein as acceptor[edit]

EC 1.12.98 With other known acceptors[edit]

EC 1.12.99 With other acceptors[edit]

EC 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)[edit]

EC 1.13.1 (transferred to EC 1.13.11)[edit]

EC 1.13.11 With incorporation of two atoms of oxygen[edit]

EC 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)[edit]

EC 1.13.99 Miscellaneous[edit]

EC 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen[edit]

EC 1.14.1 With NADH or NADPH as one donor (deleted sub-subclass)[edit]

EC 1.14.2 With ascorbate as one donor (deleted sub-subclass)[edit]

EC 1.14.3 With reduced pteridine as one donor (deleted sub-subclass)[edit]

EC 1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors[edit]

EC 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor[edit]

EC 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen[edit]

EC 1.1.2 With a cytochrome as acceptor[edit]

EC 1.1.3 With oxygen as acceptor[edit]

EC 1.1.4 With a disulfide as acceptor[edit]

EC 1.1.5 With a quinone or similar compound as acceptor[edit]

EC 1.1.9 With a copper protein as acceptor[edit]

EC 1.1.98 With other, known, acceptors[edit]

EC 1.1.99 With other acceptors[edit]

EC 1.2 Acting on the aldehyde or oxo group of donors[edit]

EC 1.2.1 With NAD or NADP as acceptor[edit]

EC 1.2.2 With a cytochrome as acceptor[edit]

EC 1.2.3 With oxygen as acceptor[edit]

EC 1.2.4 With a disulfide as acceptor[edit]


EC 1.2.5 With FAD as acceptor[edit]

EC 1.2.7 With an iron-sulfur protein as acceptor[edit]

EC 1.2.99 With other acceptors[edit]

EC 1.3 Acting on the CH-CH group of donors[edit]

EC 1.3.1 With NAD or NADP as acceptor[edit]

EC 1.3.2 With a cytochrome as acceptor[edit]

EC 1.3.3 With oxygen as acceptor[edit]

EC 1.3.5 With a quinone or related compound as acceptor[edit]

EC 1.3.7 With an iron-sulfur protein as acceptor[edit]

EC 1.3.8 With an FAD as prosthetic group[edit]

EC 1.3.98 With FMN acceptor[edit]

EC 1.3.99 With other acceptors[edit]

EC 1.4 Acting on the CH-NH2 group of donors[edit]

EC 1.4.1 With NAD or NADP as acceptor[edit]

EC 1.4.2 With a cytochrome as acceptor[edit]

EC 1.4.3 With oxygen as acceptor[edit]

EC 1.4.4 With a disulfide as acceptor[edit]

EC 1.4.5 With an iron-sulfur flavoprotein as acceptor[edit]

EC 1.4.7 With an iron-sulfur protein as acceptor[edit]

EC 1.4.9 With TTQ acceptors[edit]

EC 1.4.98 With tryptophan tryptophylquinone acceptors[edit]

EC 1.4.99 With other acceptors[edit]

EC 1.5 Acting on the CH-NH group of donors[edit]

EC 1.5.1 With NAD or NADP as acceptor[edit]

EC 1.5.3 With oxygen as acceptor[edit]

EC 1.5.4 With a disulfide as acceptor[edit]

EC 1.5.5 With a quinone or similar compound as acceptor[edit]

EC 1.5.7 With an iron-sulfur protein as acceptor[edit]

EC 1.5.8 With a flavin as acceptor[edit]

EC 1.5.99 With other acceptors[edit]

EC 1.6 Acting on NADH or NADPH[edit]

EC 1.6.1 With NAD or NADP as acceptor[edit]

EC 1.6.2 With a heme protein as acceptor[edit]

EC 1.6.3 With oxygen as acceptor[edit]

EC 1.6.4 With a disulfide as acceptor[edit]

EC 1.6.5 With a quinone or similar compound as acceptor[edit]

EC 1.6.6 With a nitrogenous group as acceptor[edit]

EC 1.6.7 With an iron-sulfur protein as acceptor[edit]

EC 1.6.8 With a flavin as acceptor[edit]

EC 1.6.99 With other acceptors[edit]

EC 1.7 Acting on other nitrogenous compounds as donors[edit]

EC 1.7.1 With NAD+ or NADP+ as acceptor[edit]

EC 1.7.2 With a cytochrome as acceptor[edit]

EC 1.7.3 With oxygen as acceptor[edit]

EC 1.7.5 With miscellaneous acceptors[edit]

EC 1.7.6 With hydrogen as acceptor[edit]

EC 1.7.7 With an iron-sulfur protein as acceptor[edit]

EC 1.7.99 With other acceptors[edit]

EC 1.8 Acting on a sulfur group of donors[edit]

EC 1.8.1 With NAD or NADP as acceptor[edit]

EC 1.8.2 With a cytochrome as acceptor[edit]

EC 1.8.3 With oxygen as acceptor[edit]

EC 1.8.4 With a disulfide as acceptor[edit]

EC 1.8.5 With a quinone or similar compound as acceptor[edit]

EC 1.8.6 With a nitrogenous group as acceptor[edit]

EC 1.8.7 With an iron-sulfur protein as acceptor[edit]

EC 1.8.98 With other, known, acceptors[edit]

EC 1.8.99 With other acceptors[edit]

EC 1.9 Acting on a heme group of donors[edit]

EC 1.9.3 With oxygen as acceptor[edit]

EC 1.9.6 With a nitrogenous group as acceptor[edit]

EC 1.9.99 With other acceptors[edit]

EC 1.10 Acting on diphenols and related substances as donors[edit]

EC 1.10.1 With NAD or NADP as acceptor[edit]

EC 1.10.2 With a cytochrome as acceptor[edit]

EC 1.10.3 With oxygen as acceptor[edit]

EC 1.10.99 With plastocyanin acceptors[edit]

EC 1.10.99 With other acceptors[edit]

EC 1.11 Acting on a peroxide as acceptor[edit]

EC 1.11.1 Peroxidases[edit]

EC 1.11.2 Peroxygenase[edit]

EC 1.12 Acting on hydrogen as donor[edit]

EC 1.12.1 With NAD or NADP as acceptor[edit]

EC 1.12.2 With a cytochrome as acceptor[edit]

EC 1.12.5 With a quinone or similar compound as acceptor[edit]

EC 1.12.7 With an iron-sulfur protein as acceptor[edit]

EC 1.12.98 With other known acceptors[edit]

EC 1.12.99 With other acceptors[edit]

EC 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)[edit]

EC 1.13.1 (transferred to EC 1.13.11)[edit]

EC 1.13.11 With incorporation of two atoms of oxygen[edit]

EC 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)[edit]

EC 1.13.99 Miscellaneous[edit]

EC 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen[edit]

EC 1.14.1 With NADH or NADPH as one donor (deleted sub-subclass)[edit]

EC 1.14.2 With ascorbate as one donor (deleted sub-subclass)[edit]

EC 1.14.3 With reduced pteridine as one donor (deleted sub-subclass)[edit]

EC 1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors[edit]

EC 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor[edit]

EC 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen[edit]