3D model (JSmol)
|Melting point||120 to 121 °C (248 to 250 °F; 393 to 394 K)|
|Boiling point||260 °C (500 °F; 533 K)|
|Flash point||140 °C (284 °F; 413 K)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
1,2,4-Triazole (as ligand in coordination compounds, Htrz abbreviation is sometimes used) is one of a pair of isomeric chemical compounds with molecular formula C2H3N3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms. 1,2,4-Triazole is a basic aromatic heterocycle. 1,2,4-Triazole derivatives find use in a wide variety of applications, most notably as antifungals such as fluconazole and itraconazole.  1,2,4-Triazoles can be prepared using the Einhorn–Brunner reaction or the Pellizzari reaction.
Unsubstituted 1,2,4-triazole can be prepared from thiosemicarbazide by acylation with formic acid followed by cyclization of 1-formyl-3-thiosemicarbazide into 1,2,4-triazole-3(5)-thiol; oxydation of thiol by nitric acid yields 1,2,4-triazole.
The ring structure appears in certain N-heterocyclic carbenes.
Used in the preparation of a plenty of pharmaceuticals: