IGHA2

IGHA2
Identifiers
Aliases	IGHA2, immunoglobulin heavy constant alpha 2 (A2m marker)
External IDs	OMIM: 147000; GeneCards: IGHA2; OMA:IGHA2 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) Band 14q32.33 Start 105,583,731 bp End 105,588,395 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon duodenum rectum appendix tonsil olfactory zone of nasal mucosa spleen bone marrow cells epithelium of colon salivary gland n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 3494 n/a Ensembl ENSG00000211890 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 14: 105.58 – 105.59 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Ig alpha-2 chain C region is a protein that in humans is encoded by the IGHA2 gene.

Further reading

• Kerr MA (Oct 1990). "The structure and function of human IgA". The Biochemical Journal. 271 (2): 285–96. doi:10.1042/bj2710285. PMC 1149552. PMID 2241915.
• Tsuzukida Y, Wang CC, Putnam FW (Mar 1979). "Structure of the A2m(1) allotype of human IgA--a recombinant molecule". Proceedings of the National Academy of Sciences of the United States of America. 76 (3): 1104–8. Bibcode:1979PNAS...76.1104T. doi:10.1073/pnas.76.3.1104. PMC 383197. PMID 286295.
• Toraño A, Putnam FW (Feb 1978). "Complete amino acid sequence of the alpha 2 heavy chain of a human IgA2 immunoglobulin of the A2m (2) allotype". Proceedings of the National Academy of Sciences of the United States of America. 75 (2): 966–9. Bibcode:1978PNAS...75..966T. doi:10.1073/pnas.75.2.966. PMC 411380. PMID 416441.
• Ellison J, Buxbaum J, Hood L (1983). "Nucleotide sequence of a human immunoglobulin C gamma 4 gene". DNA. 1 (1): 11–8. doi:10.1089/dna.1.1981.1.11. PMID 6299662.
• Ueda S, Nakai S, Nishida Y, Hisajima H, Honjo T (1984). "Long terminal repeat-like elements flank a human immunoglobulin epsilon pseudogene that lacks introns". The EMBO Journal. 1 (12): 1539–44. doi:10.1002/j.1460-2075.1982.tb01352.x. PMC 553248. PMID 6327276.
• Hisajima H, Nishida Y, Nakai S, Takahashi N, Ueda S, Honjo T (May 1983). "Structure of the human immunoglobulin C epsilon 2 gene, a truncated pseudogene: implications for its evolutionary origin". Proceedings of the National Academy of Sciences of the United States of America. 80 (10): 2995–9. doi:10.1073/pnas.80.10.2995. PMC 393960. PMID 6407005.
• Flanagan JG, Lefranc MP, Rabbitts TH (Mar 1984). "Mechanisms of divergence and convergence of the human immunoglobulin alpha 1 and alpha 2 constant region gene sequences". Cell. 36 (3): 681–8. doi:10.1016/0092-8674(84)90348-9. PMID 6421489. S2CID 54312675.
• Ellison J, Hood L (Mar 1982). "Linkage and sequence homology of two human immunoglobulin gamma heavy chain constant region genes" (PDF). Proceedings of the National Academy of Sciences of the United States of America. 79 (6): 1984–8. Bibcode:1982PNAS...79.1984E. doi:10.1073/pnas.79.6.1984. PMC 346106. PMID 6804948.
• Flanagan JG, Rabbitts TH (Dec 1982). "Arrangement of human immunoglobulin heavy chain constant region genes implies evolutionary duplication of a segment containing gamma, epsilon and alpha genes". Nature. 300 (5894): 709–13. doi:10.1038/300709a0. PMID 6817141. S2CID 4335031.
• Bunkenborg J, Pilch BJ, Podtelejnikov AV, Wiśniewski JR (Feb 2004). "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry". Proteomics. 4 (2): 454–65. doi:10.1002/pmic.200300556. PMID 14760718. S2CID 29261009.
• Kristiansen TZ, Bunkenborg J, Gronborg M, Molina H, Thuluvath PJ, Argani P, Goggins MG, Maitra A, Pandey A (Jul 2004). "A proteomic analysis of human bile". Molecular & Cellular Proteomics. 3 (7): 715–28. doi:10.1074/mcp.M400015-MCP200. PMID 15084671.
• Ramachandran P, Boontheung P, Xie Y, Sondej M, Wong DT, Loo JA (Jun 2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry". Journal of Proteome Research. 5 (6): 1493–503. doi:10.1021/pr050492k. PMID 16740002.
• Bernhard OK, Kapp EA, Simpson RJ (Mar 2007). "Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides". Journal of Proteome Research. 6 (3): 987–95. doi:10.1021/pr0604559. PMID 17330941.