Amosan
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Amosan[1] is an oral antiseptic rinse. It contains 68.635% sodium perborate monohydrate by weight. Sold as a powder customarily packaged in 1.7g envelopes, it reconstitution with warm water, after which it is used as a mouth rinse. It is used to aid in the prevention of, as well as speed the recovery from canker sores, denture irritation, orthodontic irritation, and oral injuries or after dental procedures.
History
Amosan was originally made by Oral-B; a mention of the powder appeared in the February 6, 1970 Federal Register.[2] Between 2005 and 2010, Amosan was manufactured in Belgium and sold under the Oral-B brand, belonging to Procter & Gamble after its 2005 acquisition of Gillette. In December 2010, its use was banned in the EU, as the product is based on borate, which the union considers "carcinogenic, mutagenic, or toxic for reproduction".[3]
Vintage Brands Limited began manufacturing and selling Amosan Oral Antiseptic Rinse in 2014 because many consumers were disappointed that it was no longer available.[4] Product review pages on Amazon[5] and public comment forums elsewhere[6] indicate a high level of frustration with the discontinuation by users who could find no effective alternative treatment.
A similar, if not identical product, also manufactured under the Oral-B brand name, called Bocasan was once distributed in the UK, but appears to have been discontinued some time after 2003.[citation needed]
In April 2012, it was reported that Shoppers Drug Mart in Canada had produced a comparable product under their house brand: 'Life Brand Oral Wound Cleanser'.[7] Also, Jean Coutu and Rexall has their own house brand versions.
Mechanism of action
The active ingredient, sodium perborate monohydrate, is quickly hydrolyzed into hydrogen peroxide and borate on contact with water.[8]
An 1979 recent double-blind crossover study[9] suggests that hydrogen peroxide, which is released during the use of this product, may prevent or retard colonization and multiplication of anaerobic bacteria, such as those that inhabit oral wounds.
Drug facts
- Active ingredient: Sodium perborate monohydrate 1.2 g
- Inactive ingredients: L-Tartaric acid, sodium saccharin, flavors
- Purpose: Oral wound cleanser
- Normal use: Use up to 4 times daily, after meals and before bedtime or as directed by a dentist or physician
References
- ^ "Home". amosan.ca.
- ^ Federal register
- ^ Nature Inc. (2015): "Chemical used in beauty salon teeth whitening banned by EU". BDJ Team, volume 2, article 15075, 26 June 2015. doi:10.1038/bdjteam.2015.75
- ^ Amosan Oral Products Facebook [user-generated source]
- ^ "Amosan Oral Wound Cleanser Powder". Amazon.com. Amazon.
- ^ "Bocasan/Amosan". Mouthulcers.org.
- ^ "Life Brand Oral Wound Cleanser Mouthwash 1.7g x 20 Sachets SKU 057800802228". Shopper Drug Mart / Pharmaprix. Archived from the original on 2016-03-04. Retrieved 2014-09-25.
- ^ B.J. Brotherton "Boron: Inorganic Chemistry" in Encyclopedia of Inorganic Chemistry (1994) Ed. R. Bruce King, John Wiley & Sons ISBN 0-471-93620-0
- ^ Wennstrom, Jan; Lindhe, Jan (Apr 1979). "Effect of hydrogen peroxide on developing plaque and gingivitis in man". J Clin Periodontol. 6 (2): 115–30. doi:10.1111/j.1600-051x.1979.tb02190.x. PMID 379049.
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