RRP1B

RRP1B
Identifiers
Aliases	RRP1B, KIAA0179, NNP1L, Nnp1, PPP1R136, RRP1, ribosomal RNA processing 1B
External IDs	OMIM: 610654; MGI: 1919712; HomoloGene: 57086; GeneCards: RRP1B; OMA:RRP1B - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	43,696,079 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	32,281,839 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; gingival epithelium; ; visceral pleura; ; parietal pleura; ; tibia; ; retinal pigment epithelium; ; endothelial cell; ; tendon of biceps brachii; ; skin of hip; ; mucosa of paranasal sinus;
	Top expressed in
	tail of embryo; ; neural layer of retina; ; Rostral migratory stream; ; primitive streak; ; genital tubercle; ; epiblast; ; embryo; ; morula; ; embryo; ; blastocyst;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	RNA binding; transcription coactivator activity; protein binding;
Cellular component	heterochromatin; preribosome, small subunit precursor; cytosol; euchromatin; nucleolus; nucleus; preribosome, large subunit precursor; granular component; nucleoplasm; chromosome;
Biological process	negative regulation of phosphatase activity; rRNA processing; negative regulation of GTPase activity; positive regulation of apoptotic process; regulation of RNA splicing; positive regulation of transcription by RNA polymerase II; cellular response to virus; mRNA processing; apoptotic process; RNA splicing;
	Sources:Amigo / QuickGO
Orthologs
	23076
	72462
	ENSG00000160208
	ENSMUSG00000058392
	Q14684
	Q91YK2
	NM_015056
	NM_001163734; NM_028244
	NP_055871
	NP_001157206; NP_082520
	Wikidata
View/Edit Human	View/Edit Mouse

Ribosomal RNA processing protein 1 homolog B is a protein encoded by RRP1B gene^[5] which is located on Chromosome 21.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000160208 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000058392 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: KIAA0179 KIAA0179".

Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (October 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Hu YH, Warnatz HJ, Vanhecke D, Wagner F, Fiebitz A, Thamm S, Kahlem P, Lehrach H, Yaspo ML, Janitz M (June 2006). "Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins". BMC Genomics. 7: 155. doi:10.1186/1471-2164-7-155. PMC 1526728. PMID 16780588.{{cite journal}}: CS1 maint: unflagged free DOI (link)
Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R (April 2006). "Phosphoproteome analysis of the human mitotic spindle". Proceedings of the National Academy of Sciences of the United States of America. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (January 2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Lehner B, Sanderson CM (July 2004). "A protein interaction framework for human mRNA degradation". Genome Research. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, Greco A, Hochstrasser D, Diaz JJ (November 2002). "Functional proteomic analysis of human nucleolus". Molecular Biology of the Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (January 2002). "Directed proteomic analysis of the human nucleolus". Current Biology. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Nagase T, Seki N, Ishikawa K, Tanaka A, Nomura N (February 1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA Research. 3 (1): 17–24. doi:10.1093/dnares/3.1.17. PMID 8724849.

This article on a gene on human chromosome 21 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000160208 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000058392 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: KIAA0179 KIAA0179".

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References

Further reading