Chromatin accessibility complex 1

CHRAC1
Identifiers
Aliases	CHRAC1, CHARC1, CHARC15, CHRAC-1, CHRAC-15, CHRAC15, YCL1, chromatin accessibility complex 1, chromatin accessibility complex subunit 1
External IDs	OMIM: 607268; MGI: 2135796; HomoloGene: 41174; GeneCards: CHRAC1; OMA:CHRAC1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	140,517,154 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	72,969,403 bp
RNA expression pattern
	Top expressed in
	pancreatic epithelial cell; ; monocyte; ; tibial arteries; ; muscle of leg; ; gastrocnemius muscle; ; muscle of thigh; ; tibialis anterior muscle; ; smooth muscle tissue; ; mucosa of ileum; ; right coronary artery;
	Top expressed in
	saccule; ; otic placode; ; seminiferous tubule; ; spermatocyte; ; otic vesicle; ; spermatid; ; fossa; ; condyle; ; muscle of thigh; ; intercostal muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; DNA binding; DNA-directed DNA polymerase activity; nucleotidyltransferase activity; protein binding; protein heterodimerization activity;
Cellular component	epsilon DNA polymerase complex; nucleus; CHRAC;
Biological process	DNA biosynthetic process; chromatin remodeling;
	Sources:Amigo / QuickGO
Orthologs
	54108
	93696
	ENSG00000104472
	ENSMUSG00000068391
	Q9NRG0
	Q9JKP8
	NM_017444
	NM_053068
	NP_059140
	NP_444298
	Wikidata
View/Edit Human	View/Edit Mouse

Chromatin accessibility complex 1 is a protein that in humans is encoded by the CHRAC1 gene. ^[5]

Function

CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000104472 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000068391 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Chromatin accessibility complex 1". Retrieved 2016-10-26.

Function

References

Further reading