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Acetophenone carboxylase

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Acetophenone carboxylase
Identifiers
EC no.6.4.1.8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

Acetophenone carboxylase (EC 6.4.1.8) is an enzyme with systematic name acetophenone:carbon-dioxide ligase (ADP-forming).[1] This enzyme catalyses the following chemical reaction

2 ATP + acetophenone + HCO3 + H2O + H+ 2 ADP + 2 phosphate + 3-oxo-3-phenylpropanoate

The enzyme is involved in anaerobic degradation of ethylbenzene.

References

  1. ^ Jobst B, Schühle K, Linne U, Heider J (March 2010). "ATP-dependent carboxylation of acetophenone by a novel type of carboxylase". Journal of Bacteriology. 192 (5): 1387–94. doi:10.1128/jb.01423-09. PMC 2820866. PMID 20047908.