Phosphoglucomutase (glucose-cofactor)
| phosphoglucomutase (glucose-cofactor) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 5.4.2.5 | ||||||||
| CAS no. | 37278-22-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a phosphoglucomutase (glucose-cofactor) (EC 5.4.2.5) is an enzyme that catalyzes the chemical reaction
- alpha-D-glucose 1-phosphate ⇌ D-glucose 6-phosphate
Hence, this enzyme has one substrate, alpha-D-glucose 1-phosphate, and one product, D-glucose 6-phosphate.
This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The systematic name of this enzyme class is alpha-D-glucose 1,6-phosphomutase (glucose-cofactor). Other names in common use include glucose phosphomutase, and glucose-1-phosphate phosphotransferase. This enzyme has at least one effector, D-Glucose.
References
- FUJIMOTO A, INGRAM P, SMITH RA (1965). "D-GLUCOSE-I-PHOSPHATE:D-GLUCOSE-6-PHOSPHOTRANSFERASE". Biochim. Biophys. Acta. 96: 91–101. doi:10.1016/0005-2787(65)90613-1. PMID 14285271.
- Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 6, 1972, p. 407-477.
