From Wikipedia, the free encyclopedia
Contactin 6 is a protein in humans that is encoded by the CNTN6 gene .[ 4]
The protein encoded by this gene is a member of the immunoglobulin superfamily . It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system.
References
Further reading
Manderson EN, Birch AH, Shen Z, Mes-Masson AM, Provencher D, Tonin PN (May 2009). "Molecular genetic analysis of a cell adhesion molecule with homology to L1CAM, contactin 6, and contactin 4 candidate chromosome 3p26pter tumor suppressor genes in ovarian cancer". International Journal of Gynecological Cancer . 19 (4): 513–25. doi :10.1111/IGC.0b013e3181a3cd38 . PMID 19509545 . Wang K, Zhang H, Bloss CS, Duvvuri V, Kaye W, Schork NJ, Berrettini W, Hakonarson H (September 2011). "A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa" (PDF) . Molecular Psychiatry . 16 (9): 949–59. doi :10.1038/mp.2010.107 . PMC 3859494 PMID 21079607 . Barber MJ, Mangravite LM, Hyde CL, Chasman DI, Smith JD, McCarty CA, Li X, Wilke RA, Rieder MJ, Williams PT, Ridker PM, Chatterjee A, Rotter JI, Nickerson DA, Stephens M, Krauss RM (March 2010). Zanger U (ed.). "Genome-wide association of lipid-lowering response to statins in combined study populations" . PLOS ONE . 5 (3): e9763. doi :10.1371/journal.pone.0009763 . PMC 2842298 PMID 20339536 . {{cite journal }}: CS1 maint: unflagged free DOI (link )Kamei Y, Tsutsumi O, Taketani Y, Watanabe K (February 1998). "cDNA cloning and chromosomal localization of neural adhesion molecule NB-3 in human". Journal of Neuroscience Research . 51 (3): 275–83. doi :10.1002/(SICI)1097-4547(19980201)51:3<275::AID-JNR1>3.0.CO;2-D . PMID 9486763 . Walsh FS, Doherty P (November 1991). "Glycosylphosphatidylinositol anchored recognition molecules that function in axonal fasciculation, growth and guidance in the nervous system". Cell Biology International Reports . 15 (11): 1151–66. doi :10.1016/0309-1651(91)90061-M . PMID 1838307 . Nie DY, Zhou ZH, Ang BT, Teng FY, Xu G, Xiang T, Wang CY, Zeng L, Takeda Y, Xu TL, Ng YK, Faivre-Sarrailh C, Popko B, Ling EA, Schachner M, Watanabe K, Pallen CJ, Tang BL, Xiao ZC (November 2003). "Nogo-A at CNS paranodes is a ligand of Caspr: possible regulation of K(+) channel localization" . The EMBO Journal . 22 (21): 5666–78. doi :10.1093/emboj/cdg570 . PMC 275427 PMID 14592966 . Saus E, Brunet A, Armengol L, Alonso P, Crespo JM, Fernández-Aranda F, Guitart M, Martín-Santos R, Menchón JM, Navinés R, Soria V, Torrens M, Urretavizcaya M, Vallès V, Gratacòs M, Estivill X (October 2010). "Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients" . Journal of Psychiatric Research . 44 (14): 971–8. doi :10.1016/j.jpsychires.2010.03.007 . PMID 20398908 .
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