Isocitrate epimerase
| isocitrate epimerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 5.1.2.6 | ||||||||
| CAS no. | 81210-68-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an isocitrate epimerase (EC 5.1.2.6) is an enzyme that catalyzes the chemical reaction
- (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate (1S,2S)-1-hydroxypropane-1,2,3-tricarboxylate
Hence, this enzyme has one substrate, (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate, and one product, (1S,2S)-1-hydroxypropane-1,2,3-tricarboxylate.
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on hydroxy acids and derivatives. The systematic name of this enzyme class is (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate 1-epimerase.
References
- Hoshiko S, Kunimoto Y, Arima K, Beppu T (1982). "Mechanism of L-alloisocitric acid fermentation: isocitrate epimerase activity in the cell-free-extract of Penicillium purpurogenum". Agric. Biol. Chem. 46: 143–151. doi:10.1271/bbb1961.46.143.
