RDH14

RDH14
Identifiers
Aliases	RDH14, PAN2, SDR7C4, retinol dehydrogenase 14 (all-trans/9-cis/11-cis), retinol dehydrogenase 14
External IDs	OMIM: 616796; MGI: 1920402; HomoloGene: 75139; GeneCards: RDH14; OMA:RDH14 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	18,560,679 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	10,445,562 bp
RNA expression pattern
	Top expressed in
	left ventricle; ; islet of Langerhans; ; right auricle; ; gastrocnemius muscle; ; skeletal muscle tissue; ; Achilles tendon; ; smooth muscle tissue; ; muscle of thigh; ; thoracic aorta; ; ascending aorta;
	Top expressed in
	interventricular septum; ; sternocleidomastoid muscle; ; masseter muscle; ; digastric muscle; ; triceps brachii muscle; ; temporal muscle; ; intercostal muscle; ; epithelium of lens; ; extraocular muscle; ; vastus lateralis muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	alcohol dehydrogenase (NADP+) activity; oxidoreductase activity; NADP-retinol dehydrogenase activity; steroid dehydrogenase activity;
Cellular component	lysosomal membrane; endoplasmic reticulum; mitochondrion; nucleus; endoplasmic reticulum membrane; membrane;
Biological process	retinol metabolic process; osteoblast differentiation;
	Sources:Amigo / QuickGO
Orthologs
	57665
	105014
	ENSG00000240857
	ENSMUSG00000020621
	Q9HBH5
	Q9ERI6
	NM_020905
	NM_023697
	NP_065956
	NP_076186
	Wikidata
View/Edit Human	View/Edit Mouse

Retinol dehydrogenase 14 is an enzyme that in humans is encoded by the RDH14 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000240857 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020621 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Haeseleer F, Jang GF, Imanishi Y, Driessen CA, Matsumura M, Nelson PS, Palczewski K (Nov 2002). "Dual-substrate Specificity Short Chain Retinol Dehydrogenases from the Vertebrate Retina". J Biol Chem. 277 (47): 45537–46. doi:10.1074/jbc.M208882200. PMC 1435693. PMID 12226107.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (Short-Chain Dehydrogenase/Reductase and Related Enzymes) Nomenclature Initiative". Chem Biol Interact. 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726.
^ "Entrez Gene: RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)".

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Simpson JC; Wellenreuther R; Poustka A; et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Belyaeva OV, Kedishvili NY (2002). "Human pancreas protein 2 (PAN2) has a retinal reductase activity and is ubiquitously expressed in human tissues". FEBS Lett. 531 (3): 489–93. doi:10.1016/S0014-5793(02)03588-3. PMID 12435598.
Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Clark HF; Gurney AL; Abaya E; et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Ota T; Suzuki Y; Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Wiemann S; Arlt D; Huber W; et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Mehrle A; Rosenfelder H; Schupp I; et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000240857 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020621 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12226107-5] Haeseleer F, Jang GF, Imanishi Y, Driessen CA, Matsumura M, Nelson PS, Palczewski K (Nov 2002). "Dual-substrate Specificity Short Chain Retinol Dehydrogenases from the Vertebrate Retina". J Biol Chem. 277 (47): 45537–46. doi:10.1074/jbc.M208882200. PMC 1435693. PMID 12226107.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[pmid19027726-6] Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (Short-Chain Dehydrogenase/Reductase and Related Enzymes) Nomenclature Initiative". Chem Biol Interact. 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726.

[entrez-7] "Entrez Gene: RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)".

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[3]

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[5]

[6]

[7]

References

Further reading