SARNP

SARNP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DO1
Identifiers
Aliases	SARNP, CIP29, HCC1, HSPC316, THO1, SAP domain containing ribonucleoprotein
External IDs	OMIM: 610049; MGI: 1913368; HomoloGene: 41628; GeneCards: SARNP; OMA:SARNP - orthologs
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	128,877,629 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; smooth muscle tissue; ; Achilles tendon; ; monocyte; ; tibial nerve; ; right adrenal gland; ; ascending aorta; ; islet of Langerhans; ; gastrocnemius muscle; ; left coronary artery;
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; epiblast; ; lens; ; neural tube; ; yolk sac; ; ovary; ; thymus; ; embryo; ; embryo;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; RNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein C-terminus binding; RS domain binding;
Cellular component	nuclear speck; transcription export complex; nucleus; nucleoplasm; cytoplasmic ribonucleoprotein granule;
Biological process	mRNA transport; regulation of transcription, DNA-templated; regulation of translation; transcription, DNA-templated; RNA export from nucleus; mRNA export from nucleus; termination of RNA polymerase II transcription; mRNA 3'-end processing; transport; negative regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	84324
	66118
	n/a
	ENSMUSG00000078427
	P82979
	Q9D1J3
	NM_033082
	NM_025364
	NP_149073
NP_079640; NP_001346332; NP_001346333; NP_001346334; NP_001346335;
	NP_001346336
	Wikidata
View/Edit Human	View/Edit Mouse

SAP domain-containing ribonucleoprotein is a protein that in humans is encoded by the SARNP gene.^[4]^[5]^[6]

References

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000078427 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Choong ML, Tan LK, Lo SL, Ren EC, Ou K, Ong SE, Liang RC, Seow TK, Chung MC (May 2001). "An integrated approach in the discovery and characterization of a novel nuclear protein over-expressed in liver and pancreatic tumors". FEBS Lett. 496 (2–3): 109–16. doi:10.1016/S0014-5793(01)02409-7. PMID 11356193.
^ Fukuda S, Wu DW, Stark K, Pelus LM (Mar 2002). "Cloning and characterization of a proliferation-associated cytokine-inducible protein, CIP29". Biochem Biophys Res Commun. 292 (3): 593–600. doi:10.1006/bbrc.2002.6680. PMID 11922608.
^ "Entrez Gene: CIP29 cytokine induced protein 29 kDa".

External links

Human SARNP genome location and SARNP gene details page in the UCSC Genome Browser.

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Lehner B, Semple JI, Brown SE, et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID 14667819.
Navakauskiene R, Treigyte G, Gineitis A, Magnusson KE (2004). "Identification of apoptotic tyrosine-phosphorylated proteins after etoposide or retinoic acid treatment". Proteomics. 4 (4): 1029–41. doi:10.1002/pmic.200300671. PMID 15048984.
Hashii Y, Kim JY, Sawada A, et al. (2004). "A novel partner gene CIP29 containing a SAP domain with MLL identified in infantile myelomonocytic leukemia". Leukemia. 18 (9): 1546–8. doi:10.1038/sj.leu.2403450. PMID 15284855.
Leaw CL, Ren EC, Choong ML (2004). "Hcc-1 is a novel component of the nuclear matrix with growth inhibitory function". Cell. Mol. Life Sci. 61 (17): 2264–73. doi:10.1007/s00018-004-4205-x. PMID 15338056.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Sugiura T, Sakurai K, Nagano Y (2007). "Intracellular characterization of DDX39, a novel growth-associated RNA helicase". Exp. Cell Res. 313 (4): 782–90. doi:10.1016/j.yexcr.2006.11.014. PMID 17196963.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000078427 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11356193-4] Choong ML, Tan LK, Lo SL, Ren EC, Ou K, Ong SE, Liang RC, Seow TK, Chung MC (May 2001). "An integrated approach in the discovery and characterization of a novel nuclear protein over-expressed in liver and pancreatic tumors". FEBS Lett. 496 (2–3): 109–16. doi:10.1016/S0014-5793(01)02409-7. PMID 11356193.

[pmid11922608-5] Fukuda S, Wu DW, Stark K, Pelus LM (Mar 2002). "Cloning and characterization of a proliferation-associated cytokine-inducible protein, CIP29". Biochem Biophys Res Commun. 292 (3): 593–600. doi:10.1006/bbrc.2002.6680. PMID 11922608.

[entrez-6] "Entrez Gene: CIP29 cytokine induced protein 29 kDa".

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[2]

[3]

[4]

[5]

[6]

References

External links

Further reading