HNRPA3

HNRNPA3
Identifiers
Aliases	HNRNPA3, 2610510D13Rik, D10S102, FBRNP, HNRPA3, heterogeneous nuclear ribonucleoprotein A3
External IDs	OMIM: 605372; MGI: 1917171; GeneCards: HNRNPA3; OMA:HNRNPA3 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	177,223,958 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	75,499,751 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; right testis; ; left testis; ; monocyte; ; Brodmann area 23; ; left ovary; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; epithelium of colon;
	Top expressed in
	tail of embryo; ; neural layer of retina; ; ventricular zone; ; habenula; ; dentate gyrus of hippocampal formation granule cell; ; lobe of cerebellum; ; cerebellar vermis; ; superior cervical ganglion; ; ureter; ; substantia nigra;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	RNA transmembrane transporter activity; protein binding; mRNA binding; nucleic acid binding; RNA binding;
Cellular component	cytoplasm; messenger ribonucleoprotein complex; neuron projection; ribonucleoprotein granule; catalytic step 2 spliceosome; spliceosomal complex; nucleus; nucleoplasm; postsynaptic density; ribonucleoprotein complex;
Biological process	mRNA splicing, via spliceosome; mRNA processing; mRNA transport; RNA splicing; RNA metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	220988
	229279
	ENSG00000170144
	ENSMUSG00000059005
	P51991
	Q8BG05
NM_001330247; NM_001330248; NM_001330249; NM_001330250; NM_001330251;
	NM_194247; NM_001395170
	NM_053263; NM_146130; NM_198090; NM_001359971
NP_001317176; NP_001317177; NP_001317178; NP_001317179; NP_001317180;
	NP_919223
	NP_444493; NP_666242; NP_932758; NP_001346900
	Wikidata
View/Edit Human	View/Edit Mouse

Heterogeneous nuclear ribonucleoprotein A3 is a protein that in humans is encoded by the HNRNPA3 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170144 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000059005 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ma AS, Moran-Jones K, Shan J, Munro TP, Snee MJ, Hoek KS, Smith R (May 2002). "Heterogeneous nuclear ribonucleoprotein A3, a novel RNA trafficking response element-binding protein". J Biol Chem. 277 (20): 18010–20. doi:10.1074/jbc.M200050200. PMID 11886857.
^ Makeyev AV, Kim CB, Ruddle FH, Enkhmandakh B, Erdenechimeg L, Bayarsaihan D (Mar 2005). "HnRNP A3 genes and pseudogenes in the vertebrate genomes". J Exp Zool a Comp Exp Biol. 303 (4): 259–71. doi:10.1002/jez.a.164. PMID 15776420.
^ "Entrez Gene: HNRPA3 heterogeneous nuclear ribonucleoprotein A3".

Lairmore TC, Dou S, Howe JR, et al. (1993). "A 1.5-megabase yeast artificial chromosome contig from human chromosome 10q11.2 connecting three genetic loci (RET, D10S94, and D10S102) closely linked to the MEN2A locus". Proc. Natl. Acad. Sci. U.S.A. 90 (2): 492–6. doi:10.1073/pnas.90.2.492. PMC 45689. PMID 8093642.
Takiguchi S, Tokino T, Imai T, et al. (1993). "Identification and characterization of a cDNA, which is highly homologous to the ribonucleoprotein gene, from a locus (D10S102) closely linked to MEN2 (multiple endocrine neoplasia type 2)". Cytogenet. Cell Genet. 64 (2): 128–30. doi:10.1159/000133568. PMID 8101480.
Jurica MS, Licklider LJ, Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39. doi:10.1017/S1355838202021088. PMC 1370266. PMID 11991638.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170144 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000059005 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11886857-5] Ma AS, Moran-Jones K, Shan J, Munro TP, Snee MJ, Hoek KS, Smith R (May 2002). "Heterogeneous nuclear ribonucleoprotein A3, a novel RNA trafficking response element-binding protein". J Biol Chem. 277 (20): 18010–20. doi:10.1074/jbc.M200050200. PMID 11886857.

[pmid15776420-6] Makeyev AV, Kim CB, Ruddle FH, Enkhmandakh B, Erdenechimeg L, Bayarsaihan D (Mar 2005). "HnRNP A3 genes and pseudogenes in the vertebrate genomes". J Exp Zool a Comp Exp Biol. 303 (4): 259–71. doi:10.1002/jez.a.164. PMID 15776420.

[entrez-7] "Entrez Gene: HNRPA3 heterogeneous nuclear ribonucleoprotein A3".

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References

Further reading