PLAC1

PLAC1
Identifiers
Aliases	PLAC1, CT92, OOSP2L, placenta specific 1, OOSP2B, placenta enriched 1
External IDs	OMIM: 300296; MGI: 1926287; HomoloGene: 11039; GeneCards: PLAC1; OMA:PLAC1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	134,764,322 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	52,328,988 bp
RNA expression pattern
	Top expressed in
	placenta; ; oocyte; ; testicle; ; secondary oocyte; ; cartilage tissue; ; gonad; ; stromal cell of endometrium; ; right testis; ; left testis; ; metanephros;
	Top expressed in
	yolk sac; ; decidua; ; endocardial cushion; ; embryo; ; body wall; ; blastocyst; ; embryo; ; abdominal wall; ; primitive streak; ; morula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	molecular function;
Cellular component	extracellular region; cellular component;
Biological process	multicellular organism development; placenta development;
	Sources:Amigo / QuickGO
Orthologs
	10761
	56096
	ENSG00000170965
	ENSMUSG00000061082
	Q9HBJ0
	Q9JI83
	NM_021796; NM_001316887; NM_001316888; NM_001316889
	NM_019538; NM_001357802
	NP_001303816; NP_001303817; NP_001303818; NP_068568
	NP_062411; NP_001344731
	Wikidata
View/Edit Human	View/Edit Mouse

Placenta-specific protein 1 is a protein that in humans is encoded by the PLAC1 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170965 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000061082 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cocchia M, Huber R, Pantano S, Chen EY, Ma P, Forabosco A, Ko MS, Schlessinger D (Nov 2000). "PLAC1, an Xq26 gene with placenta-specific expression". Genomics. 68 (3): 305–12. doi:10.1006/geno.2000.6302. PMID 10995572.
^ "Entrez Gene: PLAC1 placenta-specific 1".

Fant M; Weisoly DL; Cocchia M; et al. (2003). "PLAC1, a trophoblast-specific gene, is expressed throughout pregnancy in the human placenta and modulated by keratinocyte growth factor". Mol. Reprod. Dev. 63 (4): 430–6. doi:10.1002/mrd.10200. PMID 12412044. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Ota T; Suzuki Y; Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Concu M; Banzola I; Farina A; et al. (2005). "Rapid clearance of mRNA for PLAC1 gene in maternal blood after delivery". Fetal Diagn. Ther. 20 (1): 27–30. doi:10.1159/000081365. PMID 15608456. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Massabbal E; Parveen S; Weisoly DL; et al. (2005). "PLAC1 expression increases during trophoblast differentiation: evidence for regulatory interactions with the fibroblast growth factor-7 (FGF-7) axis". Mol. Reprod. Dev. 71 (3): 299–304. doi:10.1002/mrd.20272. PMID 15803460. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Otsuki T; Ota T; Nishikawa T; et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Fujito N; Samura O; Miharu N; et al. (2007). "Increased plasma mRNAs of placenta-specific 1 (PLAC1) and glial cells-missing 1 (GCM1) in mothers with pre-eclampsia". Hiroshima J. Med. Sci. 55 (1): 9–15. PMID 16594548. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Rizzo N; Banzola I; Concu M; et al. (2007). "PLAC1 mRNA levels in maternal blood at induction of labor correlate negatively with induction-delivery interval". Eur. J. Obstet. Gynecol. Reprod. Biol. 132 (2): 177–81. doi:10.1016/j.ejogrb.2006.05.039. PMID 16860456. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Fant M; Barerra-Saldana H; Dubinsky W; et al. (2007). "The PLAC1 protein localizes to membranous compartments in the apical region of the syncytiotrophoblast". Mol. Reprod. Dev. 74 (7): 922–9. doi:10.1002/mrd.20673. PMID 17186554. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Purwosunu Y; Sekizawa A; Farina A; et al. (2007). "Cell-free mRNA concentrations of CRH, PLAC1, and selectin-P are increased in the plasma of pregnant women with preeclampsia". Prenat. Diagn. 27 (8): 772–7. doi:10.1002/pd.1780. PMID 17554801. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
Koslowski M; Sahin U; Mitnacht-Kraus R; et al. (2007). "A placenta-specific gene ectopically activated in many human cancers is essentially involved in malignant cell processes". Cancer Res. 67 (19): 9528–34. doi:10.1158/0008-5472.CAN-07-1350. PMID 17909063. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170965 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000061082 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10995572-5] Cocchia M, Huber R, Pantano S, Chen EY, Ma P, Forabosco A, Ko MS, Schlessinger D (Nov 2000). "PLAC1, an Xq26 gene with placenta-specific expression". Genomics. 68 (3): 305–12. doi:10.1006/geno.2000.6302. PMID 10995572.

[entrez-6] "Entrez Gene: PLAC1 placenta-specific 1".

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References

Further reading