Gamma-humulene synthase
Appearance
Gamma-humulene synthase | |||||||||
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Identifiers | |||||||||
EC no. | 4.2.3.56 | ||||||||
CAS no. | 110639-19-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Gamma-humulene synthase (EC 4.2.3.56, humulene cyclase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (gamma-humulene-forming).[1][2] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate gamma-humulene + diphosphate
References
- ^ Steele CL, Crock J, Bohlmann J, Croteau R (January 1998). "Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of delta-selinene synthase and gamma-humulene synthase". The Journal of Biological Chemistry. 273 (4): 2078–89. doi:10.1074/jbc.273.4.2078. PMID 9442047.
- ^ Little DB, Croteau RB (June 2002). "Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases delta-selinene synthase and gamma-humulene synthase". Archives of Biochemistry and Biophysics. 402 (1): 120–35. doi:10.1016/S0003-9861(02)00068-1. PMID 12051690.
External links
- Gamma-humulene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)