SGSM1

SGSM1
Identifiers
Aliases	SGSM1, RUTBC2, small G protein signaling modulator 1
External IDs	OMIM: 611417; MGI: 107320; HomoloGene: 64485; GeneCards: SGSM1; OMA:SGSM1 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	24,927,578 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	113,458,652 bp
RNA expression pattern
	Top expressed in
	cardiac muscle tissue of right atrium; ; Brodmann area 23; ; middle temporal gyrus; ; superior frontal gyrus; ; postcentral gyrus; ; entorhinal cortex; ; hypothalamus; ; cerebellar hemisphere; ; primary visual cortex; ; right hemisphere of cerebellum;
	Top expressed in
	superior cervical ganglion; ; arcuate nucleus; ; dorsomedial hypothalamic nucleus; ; paraventricular nucleus of hypothalamus; ; median eminence; ; lumbar subsegment of spinal cord; ; ventromedial nucleus; ; nucleus of stria terminalis; ; lateral hypothalamus; ; suprachiasmatic nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; GTPase activator activity;
Cellular component	Golgi apparatus; membrane; cytoplasm; cytoplasmic vesicle membrane; cytosol; endomembrane system; cytoplasmic vesicle;
Biological process	activation of GTPase activity; intracellular protein transport; regulation of vesicle fusion;
	Sources:Amigo / QuickGO
Orthologs
	129049
	52850
	ENSG00000167037
	ENSMUSG00000042216
	Q2NKQ1
	Q8BPQ7
	NM_133454; NM_001039948; NM_001098497; NM_001098498
	NM_001162965; NM_001254731; NM_172718; NM_001309526; NM_001309528
	NP_001035037; NP_001091967; NP_001091968; NP_597711
	NP_001156437; NP_001241660; NP_001296455; NP_001296457; NP_766306
	Wikidata
View/Edit Human	View/Edit Mouse

Small G protein signaling modulator 1 (SGSM1) also known as RUN and TBC1 domain-containing protein 2 (RUTBC2) and nurr1-interacting protein (NuIP)^[5] is a protein in humans that is encoded by the SGSM1 gene.^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167037 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042216 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Luo Y, Xing F, Guiliano R, Federoff HJ (September 2008). "Identification of a novel nurr1-interacting protein". The Journal of Neuroscience. 28 (37): 9277–86. doi:10.1523/JNEUROSCI.3021-08.2008. PMID 18784308.
^ "Entrez Gene: Small G protein signaling modulator 1".
^ Yang H, Sasaki T, Minoshima S, Shimizu N (August 2007). "Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway". Genomics. 90 (2): 249–60. doi:10.1016/j.ygeno.2007.03.013. PMID 17509819.

This article on a gene on human chromosome 22 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000167037 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000042216 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid18784308-5] Luo Y, Xing F, Guiliano R, Federoff HJ (September 2008). "Identification of a novel nurr1-interacting protein". The Journal of Neuroscience. 28 (37): 9277–86. doi:10.1523/JNEUROSCI.3021-08.2008. PMID 18784308.

[entrez-6] "Entrez Gene: Small G protein signaling modulator 1".

[Yang_2007-7] Yang H, Sasaki T, Minoshima S, Shimizu N (August 2007). "Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway". Genomics. 90 (2): 249–60. doi:10.1016/j.ygeno.2007.03.013. PMID 17509819.

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