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Pustulosis palmaris et plantaris

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Pustulosis palmaris et plantaris
Other namesPustulosis of palms and soles,[1] Palmoplantar pustulosis, Persistent palmoplantar pustulosis, Pustular psoriasis of the Barber type, and Pustular psoriasis of the extremities
Pustulosis palmaris et plantaris
SpecialtyDermatology Edit this on Wikidata
Differential diagnosisSAPHO syndrome

Pustulosis palmaris et plantaris is a chronic recurrent pustular dermatosis (that is, a pustulosis or pustular psoriasis) localized on the palms and soles only, characterized histologically by intraepidermal pustules filled with neutrophils.[2]: 411, 628 [3]: 204  It can occur as part of the SAPHO syndrome.[4]

Diagnosis

Treatment

There is lack of evidence for superpotent corticosteroids, phototherapy, acitretin, methotrexate, and ciclosporin in treating chronic palmoplantar pustulosis. However, maxacalcitol may be effective in treating such disease in short term.[5]

Treatment with guselkumab, an anti–interleukin 23 monoclonal antibody has shown a decrease in the size of the area effected and severity.[6]

See also

References

  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1. {{cite book}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
  2. ^ Freedberg, Irwin M; Fitzpatrick, Thomas B (2003). Fitzpatrick's Dermatology in General Medicine (6th ed.). McGraw-Hill. ISBN 0-07-138076-0. {{cite book}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
  3. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. ISBN 0-7216-2921-0. {{cite book}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help).
  4. ^ Matzaroglou C, Velissaris D, Karageorgos A, Marangos M, Panagiotopoulos E, Karanikolas M (November 2009). "SAPHO Syndrome Diagnosis and Treatment: Report of Five Cases and Review of the Literature". The Open Orthopaedics Journal. 3: 100–6. doi:10.2174/1874325000903010100. PMC 2790148. PMID 19997538.
  5. ^ Obeid G, Do G, Kirby L, Hughes C, Sbidian E, Le Cleach L, et al. (Cochrane Skin Group) (January 2020). "Interventions for chronic palmoplantar pustulosis". The Cochrane Database of Systematic Reviews. 1: CD011628. doi:10.1002/14651858.CD011628.pub2. PMC 6984641. PMID 31958161.
  6. ^ Terui T, Kobayashi S, Okubo Y, Murakami M, Zheng R, Morishima H, et al. (July 2019). "Efficacy and Safety of Guselkumab in Japanese Patients With Palmoplantar Pustulosis: A Phase 3 Randomized Clinical Trial". JAMA Dermatology. 155 (10): 1153. doi:10.1001/jamadermatol.2019.1394. PMC 6613288. PMID 31268476.
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