From Wikipedia, the free encyclopedia
Leucine-rich repeat and calponin homology domain-containing protein 4 is a protein that in humans is encoded by the LRCH4 gene .[ 5] [ 6]
This gene encodes a protein that contains leucine-rich repeats (LRR) at its amino terminus and that is known to be involved in ligand binding. The carboxyl terminus may act as a membrane anchor. Identified structural elements suggest that the encoded protein resembles a receptor .[ 6]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000077454 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000093445 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Glockner G, Scherer S, Schattevoy R, Boright A, Weber J, Tsui LC, Rosenthal A (Dec 1998). "Large-Scale Sequencing of Two Regions in Human Chromosome 7q22: Analysis of 650 kb of Genomic Sequence around the EPO and CUTL1 Loci Reveals 17 Genes" . Genome Res . 8 (10): 1060–73. doi :10.1101/gr.8.10.1060 . PMC 310788 PMID 9799793 . ^ a b "Entrez Gene: LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4" .
Further reading
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 . PMID 17081983 . S2CID 7827573 . Shiio Y, Rose DW, Aur R, et al. (2006). "Identification and Characterization of SAP25, a Novel Component of the mSin3 Corepressor Complex" . Mol. Cell. Biol . 26 (4): 1386–97. doi :10.1128/MCB.26.4.1386-1397.2006 . PMC 1367179 PMID 16449650 . Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology" . Science . 300 (5620): 767–72. doi :10.1126/science.1083423 . PMC 2882961 PMID 12690205 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 PMID 12477932 .
