Jump to content

Cyclopyrrolones

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by DMacks (talk | contribs) at 05:00, 3 November 2020 (→top: rm previously-listed from the "others..." list). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Skeletal formula of the parent compound, cyclopyrrolone

Cyclopyrrolones are a family of hypnotic and anxiolytic nonbenzodiazepine drugs with similar pharmacological profiles to the benzodiazepine derivatives.

Although cyclopyrrolones are chemically unrelated to benzodiazepines, they function via the benzodiazepine receptor of neurotransmitter GABA.[1] The best-known cyclopyrrolone derivatives are zopiclone (Imovane) and its active single-enantiomer component, eszopiclone (Lunesta), which are used to treat insomnia, and have a known potential for abuse. Other cyclopyrrolones include:

References

  1. ^ http://bmj.bmjjournals.com/cgi/content/full/316/7125/117


Stub icon

This article about a heterocyclic compound is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Cyclopyrrolones&oldid=986817034"