Goblet cell carcinoid
Appearance
Goblet cell carcinoid | |
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Other names | Crypt cell carcinoma, neuroendocrine tumour with goblet cell differentiation |
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Micrograph showing a goblet cell carcinoid. H&E stain. |
The goblet cell carcinoid (GCC) is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma, histologically arising from Paneth cells.[1]
Sign and symptoms
[edit]GCCs may present as appendicitis.
Diagnosis
[edit]![](http://upload.wikimedia.org/wikipedia/commons/thumb/3/38/Goblet_cell_carcinoid_-_very_low_mag.jpg/220px-Goblet_cell_carcinoid_-_very_low_mag.jpg)
GCCs are diagnosed by pathology. They have a characteristic biphasic appearance which includes (1) goblet cell-like cells, and (2) neuroendocrine-type nuclear chromatin (stippled chromatin).
Prognosis
[edit]GCCs have an aggressive course compared to other appendiceal neuroendocrine tumours.[1]
Treatment
[edit]GCCs are treated with surgery.
See also
[edit]References
[edit]External links
[edit]![](http://upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png)
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