USP44

USP44
Identifiers
Aliases	USP44, ubiquitin specific peptidase 44
External IDs	OMIM: 610993; MGI: 3045318; HomoloGene: 12961; GeneCards: USP44; OMA:USP44 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	95,551,476 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	93,693,950 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; sperm; ; testicle; ; left testis; ; right testis; ; buccal mucosa cell; ; lower lobe of lung; ; cerebellar hemisphere; ; tibial nerve; ; right hemisphere of cerebellum;
	Top expressed in
	spermatid; ; seminiferous tubule; ; spermatocyte; ; epiblast; ; tail of embryo; ; embryo; ; embryo; ; ventricular zone; ; primitive streak; ; thymus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; peptidase activity; cysteine-type peptidase activity; protein binding; hydrolase activity; metal ion binding; thiol-dependent deubiquitinase;
Cellular component	nucleus; nucleoplasm; cytoplasm;
Biological process	cell cycle; regulation of mitotic cell cycle spindle assembly checkpoint; ubiquitin-dependent protein catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process; proteolysis; cell division; negative regulation of ubiquitin protein ligase activity; protein deubiquitination; chromosome segregation;
	Sources:Amigo / QuickGO
Orthologs
	84101
	327799
	ENSG00000136014
	ENSMUSG00000020020
	Q9H0E7
	Q8C2S0
	NM_001042403; NM_001278393; NM_032147; NM_001347936; NM_001347937
	NM_001206851; NM_183199; NM_001376981; NM_001400981
	NP_001035862; NP_001265322; NP_115523; NP_001334865; NP_001334866
	NP_001193780; NP_001363910; NP_001387910
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 44 is an enzyme that in humans is encoded by the USP44 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136014 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020020 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. S2CID 2856065.
^ "Entrez Gene: USP44 ubiquitin specific peptidase 44".

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Quesada V, Díaz-Perales A, Gutiérrez-Fernández A, et al. (2004). "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases". Biochem. Biophys. Res. Commun. 314 (1): 54–62. doi:10.1016/j.bbrc.2003.12.050. PMID 14715245.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Stegmeier F, Rape M, Draviam VM, et al. (2007). "Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities". Nature. 446 (7138): 876–81. doi:10.1038/nature05694. PMID 17443180. S2CID 4321083.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000136014 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020020 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12838346-5] Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. S2CID 2856065.

[entrez-6] "Entrez Gene: USP44 ubiquitin specific peptidase 44".

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References

Further reading