Tetrahymanol synthase
Appearance
Tetrahymanol synthase | |||||||||
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Identifiers | |||||||||
EC no. | 4.2.1.123 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Tetrahymanol synthase (EC 4.2.1.123, squaleneatetrahymanol cyclase) is an enzyme with systematic name squalene hydro-lyase (tetrahymanol forming).[1][2] This enzyme catalyses the following chemical reaction
- tetrahymanol squalene + H2O
The reaction occurs in the reverse direction.
This enzyme is isolated from Tetrahymena protozoans.
References
- ^ Saar J, Kader JC, Poralla K, Ourisson G (September 1991). "Purification and some properties of the squalene-tetrahymanol cyclase from Tetrahymena thermophila". Biochimica et Biophysica Acta (BBA) - General Subjects. 1075 (1): 93–101. doi:10.1016/0304-4165(91)90080-z. PMID 1892870.
- ^ Giner JL, Rocchetti S, Neunlist S, Rohmer M, Arigoni D (June 2005). "Detection of 1,2-hydride shifts in the formation of euph-7-ene by the squalene-tetrahymanol cyclase of Tetrahymena pyriformis". Chemical Communications (24): 3089–91. doi:10.1039/b504300j. PMID 15959594.
External links
- Tetrahymanol+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)