WDR46

WDR46
Identifiers
Aliases	WDR46, BING4, C6orf11, FP221, UTP7, WD repeat domain 46
External IDs	OMIM: 611440; MGI: 1931871; HomoloGene: 3981; GeneCards: WDR46; OMA:WDR46 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	33,289,247 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	34,168,671 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; stromal cell of endometrium; ; anterior pituitary; ; mucosa of transverse colon; ; spleen; ; appendix; ; left testis; ; skin of leg; ; apex of heart; ; right lobe of thyroid gland;
	Top expressed in
	Gonadal ridge; ; epiblast; ; submandibular gland; ; gastrula; ; abdominal wall; ; hair follicle; ; mandibular prominence; ; Paneth cell; ; primitive streak; ; maxillary prominence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA binding;
Cellular component	small-subunit processome; nucleolus; 90S preribosome; nucleus; nucleoplasm; cellular component;
Biological process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); positive regulation of protein targeting to mitochondrion; rRNA processing;
	Sources:Amigo / QuickGO
Orthologs
	9277
	57315
ENSG00000206284; ENSG00000236222; ENSG00000204221; ENSG00000226916; ENSG00000227057;
	n/a
	ENSMUSG00000024312
	O15213
	Q9Z0H1
	NM_001164267; NM_005452
	NM_020603
	NP_001157739; NP_005443
	NP_065628
	Wikidata
View/Edit Human	View/Edit Mouse

WD repeat-containing protein 46 is a protein that in humans is encoded by the WDR46 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c ENSG00000236222, ENSG00000204221, ENSG00000226916, ENSG00000227057 GRCh38: Ensembl release 89: ENSG00000206284, ENSG00000236222, ENSG00000204221, ENSG00000226916, ENSG00000227057 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024312 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Herberg JA, Beck S, Trowsdale J (May 1998). "TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC". J Mol Biol. 277 (4): 839–57. doi:10.1006/jmbi.1998.1637. PMID 9545376.
^ Herberg JA, Sgouros J, Jones T, Copeman J, Humphray SJ, Sheer D, Cresswell P, Beck S, Trowsdale J (Mar 1998). "Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC". Eur J Immunol. 28 (2): 459–67. doi:10.1002/(SICI)1521-4141(199802)28:02<459::AID-IMMU459>3.0.CO;2-Z. PMID 9521053.
^ "Entrez Gene: WDR46 WD repeat domain 46".

Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.

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[refGRCh38Ensembl-1] ENSG00000236222, ENSG00000204221, ENSG00000226916, ENSG00000227057 GRCh38: Ensembl release 89: ENSG00000206284, ENSG00000236222, ENSG00000204221, ENSG00000226916, ENSG00000227057 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024312 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9545376-5] Herberg JA, Beck S, Trowsdale J (May 1998). "TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC". J Mol Biol. 277 (4): 839–57. doi:10.1006/jmbi.1998.1637. PMID 9545376.

[pmid9521053-6] Herberg JA, Sgouros J, Jones T, Copeman J, Humphray SJ, Sheer D, Cresswell P, Beck S, Trowsdale J (Mar 1998). "Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC". Eur J Immunol. 28 (2): 459–67. doi:10.1002/(SICI)1521-4141(199802)28:02<459::AID-IMMU459>3.0.CO;2-Z. PMID 9521053.

[entrez-7] "Entrez Gene: WDR46 WD repeat domain 46".

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[4]

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References

Further reading