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ADAM20

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ADAM 20 is a membrane disintegrin-metalloprotease that belongs to the ADAM family. It is exclusively expressed in Testes and is similar to sperm cell-specific fertilins -alpha and -beta.

Its cDNA was mapped, and was found to be tightly linked to marker SHGC-36001 on chromosome 14q24.1. ADAM 20 may be the functional equivalent of fertilin-alpha in humans.[1]

References

  1. ^ Hooft van Huijsduijnen, R. (1998-01-12). "ADAM 20 and 21; two novel human testis-specific membrane metalloproteases with similarity to fertilin-alpha". Gene. 206 (2): 273–282. doi:10.1016/s0378-1119(97)00597-0. ISSN 0378-1119. PMID 9469942.


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