ARF5

ARF5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2B6H
Identifiers
Aliases	ARF5, ADP ribosylation factor 5
External IDs	OMIM: 103188 MGI: 99434 HomoloGene: 129625 GeneCards: ARF5
Gene location (Human)
Chr.	Chromosome 7 (human)
End	127,591,700 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	28,426,601 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; Brodmann area 9; ; skin of abdomen; ; body of pancreas; ; superior frontal gyrus; ; nucleus accumbens; ; putamen; ; monocyte; ; caudate nucleus; ; right uterine tube;
	Top expressed in
	lip; ; superior frontal gyrus; ; yolk sac; ; entorhinal cortex; ; spermatocyte; ; duodenum; ; thymus; ; stomach; ; esophagus; ; intestinal villus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity;
Cellular component	cytoplasm; perinuclear region of cytoplasm; plasma membrane; Golgi apparatus; extracellular exosome; intracellular anatomical structure; membrane;
Biological process	protein transport; small GTPase mediated signal transduction; vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; transport; intracellular protein transport; Golgi to plasma membrane transport;
	Sources:Amigo / QuickGO
Orthologs
	381
	11844
	ENSG00000004059
	ENSMUSG00000020440
	P84085
	P84084
	NM_001662
	NM_007480
	NP_001653
	NP_031506
	Wikidata
View/Edit Human	View/Edit Mouse

ADP-ribosylation factor 5 is a protein that in humans is encoded by the ARF5 gene.^[5]^[6]

Interactions

ARF5 has been shown to interact with ARFIP2.^[7]^[8]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000004059 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020440 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tsuchiya M, Price SR, Tsai SC, Moss J, Vaughan M (March 1991). "Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells". J Biol Chem. 266 (5): 2772–7. PMID 1993656.
^ "Entrez Gene: ARF5 ADP-ribosylation factor 5".
^ Kanoh, H; Williger B T; Exton J H (February 1997). "Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes". J. Biol. Chem. 272 (9). UNITED STATES: 5421–9. doi:10.1074/jbc.272.9.5421. ISSN 0021-9258. PMID 9038142. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)CS1 maint: unflagged free DOI (link)
^ Shin, O H; Exton J H (August 2001). "Differential binding of arfaptin 2/POR1 to ADP-ribosylation factors and Rac1". Biochem. Biophys. Res. Commun. 285 (5). United States: 1267–73. doi:10.1006/bbrc.2001.5330. ISSN 0006-291X. PMID 11478794. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)