ATG7

ATG7
Identifiers
Aliases	ATG7, APG7-LIKE, APG7L, GSA7, autophagy related 7, SCAR31
External IDs	OMIM: 608760 MGI: 1921494 HomoloGene: 4662 GeneCards: ATG7
Gene location (Human) Chr. Chromosome 3 (human) Band 3p25.3 Start 11,272,309 bp End 11,557,665 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6|6 E3 Start 114,620,058 bp End 114,837,575 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte Achilles tendon oocyte islet of Langerhans blood rectum gallbladder stromal cell of endometrium prefrontal cortex sural nerve Top expressed in spermatocyte morula spermatid left lobe of liver secondary oocyte lip yolk sac internal carotid artery crypt of lieberkuhn of small intestine proximal tubule More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein homodimerization activity transcription factor binding ubiquitin activating enzyme activity protein binding ubiquitin-like modifier activating enzyme activity Atg12 activating enzyme activity Atg8 activating enzyme activity Cellular component cytoplasm axoneme extracellular region axon secretory granule lumen ficolin-1-rich granule lumen cytosol phagophore assembly site Biological process positive regulation of protein catabolic process cellular response to hyperoxia cellular response to starvation membrane fusion defense response to virus positive regulation of protein modification process positive regulation of apoptotic process protein transport protein lipidation suppression by virus of host autophagy protein ubiquitination autophagy human ageing response to glucose macroautophagy response to nutrient levels neutrophil degranulation negative regulation of cell death cellular response to morphine negative regulation of mitochondrial DNA replication regulation of neuron death response to fluoride negative regulation of oxidative stress-induced neuron death autophagy of mitochondrion autophagosome assembly C-terminal protein lipidation cellular response to nitrogen starvation piecemeal microautophagy of the nucleus late nucleophagy positive regulation of autophagy regulation of circadian rhythm chaperone-mediated autophagy protein modification by small protein conjugation rhythmic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10533 74244 Ensembl ENSG00000197548 ENSMUSG00000030314 UniProt O95352 Q9D906 RefSeq (mRNA) NM_001136031 NM_001144912 NM_006395 NM_001349232 NM_001349233 NM_001349234 NM_001349235 NM_001349236 NM_001349237 NM_001349238 NM_001253717 NM_001253718 NM_028835 NM_001379130 RefSeq (protein) NP_001129503 NP_001138384 NP_006386 NP_001336161 NP_001336162 NP_001336163 NP_001336164 NP_001336165 NP_001336166 NP_001336167 NP_001240646 NP_001240647 NP_083111 NP_001366059 Location (UCSC) Chr 3: 11.27 – 11.56 Mb Chr 6: 114.62 – 114.84 Mb PubMed search
Wikidata
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Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene.