ATP6V1A

ATP6V1A
Identifiers
Aliases	ATP6V1A, ATP6A1, ATP6V1A1, HO68, VA68, VPP2, Vma1, ATPase H+ transporting V1 subunit A, ARCL2D, IECEE3, DEE93
External IDs	OMIM: 607027 MGI: 1201780 HomoloGene: 123934 GeneCards: ATP6V1A
Gene location (Human)
Chr.	Chromosome 3 (human)
End	113,812,056 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	43,960,068 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; middle temporal gyrus; ; pons; ; endothelial cell; ; kidney tubule; ; orbitofrontal cortex; ; cerebellar vermis; ; renal medulla; ; frontal pole; ; superior vestibular nucleus;
	Top expressed in
	cingulate gyrus; ; ventromedial nucleus; ; primary motor cortex; ; dentate gyrus; ; facial motor nucleus; ; medial dorsal nucleus; ; medial vestibular nucleus; ; pontine nuclei; ; mammillary body; ; entorhinal cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; hydrolase activity; ATP binding; proton-transporting ATPase activity, rotational mechanism;
Cellular component	proton-transporting V-type ATPase, V1 domain; cytosol; myelin sheath; plasma membrane; proton-transporting two-sector ATPase complex; integral component of plasma membrane; microvillus; lysosomal membrane; apical plasma membrane; mitochondrion; extracellular exosome; cytoplasm; vacuolar membrane;
Biological process	insulin receptor signaling pathway; transferrin transport; ion transport; ion transmembrane transport; ATP metabolic process; regulation of macroautophagy; phagosome acidification; cellular iron ion homeostasis; cellular response to increased oxygen levels; transport; proton transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	523
	11964
	ENSG00000114573
	ENSMUSG00000052459
	P38606
	P50516
	NM_001690
	NM_007508; NM_001358203; NM_001358204
	NP_001681
	NP_031534; NP_001345132; NP_001345133
	Wikidata
View/Edit Human	View/Edit Mouse

V-type proton ATPase catalytic subunit A is an enzyme that in humans is encoded by the ATP6V1A gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000114573 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000052459 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ van Hille B, Richener H, Evans DB, Green JR, Bilbe G (May 1993). "Identification of two subunit A isoforms of the vacuolar H(+)-ATPase in human osteoclastoma". J Biol Chem. 268 (10): 7075–80. PMID 8463241.
^ "Entrez Gene: ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A".

External links

Human ATP6V1A genome location and ATP6V1A gene details page in the UCSC Genome Browser.

References

External links

Further reading