Abdominal epilepsy
| Abdominal epilepsy |
|---|
Abdominal epilepsy is a rare condition consisting of gastrointestinal (GI) disturbances caused by epileptiform seizure activity. While a causal relationship between seizure activity and the GI symptoms has not been proven, the GI symptoms cannot be explained by other pathophysiological mechanisms, and are seen to improve upon anticonvulsant treatment.
Abdominal epilepsy can be a rare cause of recurrent abdominal pain.[1][2][3][4][5] It has been described as a type of temporal lobe epilepsy.[6] Responsiveness to anticonvulsants can aid in the diagnosis.[7]
Incidence
While reliable estimates of incidence are lacking, abdominal epilepsy is considered to be a very rare condition. Most published medical literature dealing with abdominal epilepsy is in the form of individual case reports. A 2005 review article found a total of 36 cases described in the medical literature.[3]
History
Trousseau is commonly credited as the first to describe the condition in 1868 in a boy with paroxysmal GI symptoms culminating in grand mal epileptic seizures.
The first account of abdominal epilepsy supported by EEG tracings came in 1944 in an article by M.T. Moore, followed by subsequent case reports from the same group.[8][9]
References
- ^ Dutta SR, Hazarika I, Chakravarty BP (2007). "Abdominal epilepsy, an uncommon cause of recurrent abdominal pain: a brief report". Gut. 56 (3): 439–41. doi:10.1136/gut.2006.094250. PMC 1856820. PMID 17339252.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ Eschle D, Siegel AM, Wieser HG (2002). "Epilepsy with severe abdominal pain". Mayo Clin. Proc. 77 (12): 1358–60. doi:10.4065/77.12.1358. PMID 12479525.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ a b Zinkin NT, Peppercorn MA (2005). "Abdominal epilepsy". Best Pract Res Clin Gastroenterol. 19 (2): 263–74. doi:10.1016/j.bpg.2004.10.001. PMID 15833692.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Levendorf M (2000). "Chronic abdominal pain and abdominal epilepsy". Am Fam Physician. 61 (1): 50. PMID 10643951.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Peppercorn MA, Herzog AG (1989). "The spectrum of abdominal epilepsy in adults". Am. J. Gastroenterol. 84 (10): 1294–6. PMID 2801681.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Topno N, Gopasetty MS, Kudva A, B L (2005). "Abdominal Epilepsy and Foreign Body in the Abdomen - Dilemma in Diagnosis of Abdominal Pain". Yonsei Med. J. 46 (6): 870–3. doi:10.3349/ymj.2005.46.6.870. PMC 2810606. PMID 16385668.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link)[dead link] - ^ Singhi PD, Kaur S (1988). "Abdominal epilepsy misdiagnosed as psychogenic pain". Postgrad Med J. 64 (750): 281–2. doi:10.1136/pgmj.64.750.281. PMC 2428499. PMID 3186570.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ M.T. Moore, "Paroxysmal abdominal pain: a form of focal symptomatic epilepsy", JAMA.1944 124 561-563
- ^ MOORE MT (1950). "Abdominal epilepsy versus "abdominal migraine"". Ann. Intern. Med. 33 (1): 122–33. PMID 15426097.
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