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Alpha-eudesmol synthase

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Alpha-eudesmol synthase
Identifiers
EC no.4.2.3.85
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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NCBIproteins

Alpha-eudesmol synthase (EC 4.2.3.85) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (alpha-eudesmol-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O alpha-eudesmol + diphosphate

The recombinant enzyme from ginger (Zingiber zerumbet) gives beta-eudesmol, 10-epi-gamma-eudesmol, alpha-eudesmol and aristolene.

References

  1. ^ Yu, F.; Harada, H.; Yamasaki, K.; Okamoto, S.; Hirase, S.; Tanaka, Y.; Misawa, N.; Utsumi, R. (2008). "Isolation and functional characterization of a β-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith". FEBS Lett. 582: 565–572. doi:10.1016/j.febslet.2008.01.020. PMID 18242187.