Antoine Ouilmette (c. 1760–1841) was a fur trader and early resident of what is now Chicago, Illinois. He was of French Canadian and possibly Native American ancestry. The village of Wilmette, Illinois (phonetic spelling of Ouilmette) is named in his honor.
Little is known about Ouilmette's background and early life. In 1908, amateur historian Frank Grover wrote that previous claims that Ouilmette was an "Indian chief" were false, and that he was instead a white voyageur of French Canadian ancestry. However, "Ouilamette" was a name associated with the Potawatomi tribe decades before Antoine Ouilmette's birth, and so in 1977 anthropologist James A. Clifton speculated that Antoine Ouilmette was "probably a Métis descendant" of Ouilamette, a Native American who was prominent in the Lake Michigan region beginning in the 1680s. Grover wrote that Ouilmette was born in Lahndrayh, near Montréal, in 1760. Another source says that he was baptized as "Antoine Louis Ouimet", on December 26, 1758 in the parish of Sainte-Rose northwest of Montréal, in what is now the city of Laval, Québec. He was the second son of Louis Ouimet dit Albert and Louise Desjardins dit Charbonnier. It is not known why and when Antoine's family name changed to Ouilmette; also referred to as Ouilmet, Houillamette, Willamette, Wilmette, Wilmot, Wemet.
Ouilmette was employed by the American Fur Company, and moved to Chicago in July 1790 where he built a log cabin on the north side of the main branch of the Chicago River, just to the west of the property of Jean Baptiste Point du Sable and across the river from the future site of Fort Dearborn. In 1796 or 1797 he married Archange Marie Chevalier, a French-Potawatomi woman, at Gross Pointe (a site along the northern shore of Lake Michigan. He was employed by John Kinzie after Kinzie settled in Chicago in 1804.
Due to Archange being Potawatomi, Ouilmette family did not flee their home during the Battle of Fort Dearborn in 1812. After the battle, the Ouilmettes hid Margeret Helm, the wife of a lieutenant, and Sergeant William Griffith at their house, protecting them from the Potowatomi that attacked Fort Dearborn.
Ouilmette and his Métis family were friendly with most of the local native American population and so they remained in Chicago in the four years that followed the Battle of Fort Dearborn. Antoine was the only white resident during this time.
In addition to fur trading Ouilmette also worked as a farmer (supplying Fort Dearborn with livestock and cordwood). However, his income predominantly came from his work as a guide transporting people and goods across the Chicago Portage.
Ouilmette was a "progressive, energetic man of good business ability for those times, he accumulated considerable property. He had a store in Chicago, and also a fine lot of horses, cattle, sheep and hogs. He also had a farm at Racine, Wisconsin, which he frequently visited while living in Chicago. He also made occasional business trips to Milwaukee and Canada." 
Antoine and Archange had eight children, four boys and four girls: Joseph, Louis, François, Michael (aka Michell), Elizabeth, Archange, Josette, and Sophia, as well as an adopted daughter, Archange Trombola.
Ouilmette was Roman Catholic. In April 1833, he along with Alexander Robinson, Billy Caldwell, several of the Beaubiens and others, in a petition to the Bishop of the diocese of Missouri, located in St. Louis, asking for permission to establish the first Catholic church in Chicago. The petition was received on 16 April and granted the next day.
In 1829 he was instrumental in persuading local Native Americans to sign the second Treaty of Prairie du Chien
On July 29, 1829, as a condition of a treaty with the U.S. government awarded 1,280 acres (5.2 km2) of land in present-day Wilmette and Evanston to Ouilmette's wife Archange as a condition of a treaty with the Ojibwe, Odawa and Pottawatomie tribes. Elijah M. Haines claimed that the land was given to Ouilmette's wife and children as a reward for Ouilmette's influence in securing the execution of the treaty,
Shortly after this Ouilmette and his family moved to a cabin on this reservation. Ouilmette was also involved with the Treaty of Chicago (1833) negotiations. This treaty not only provided provisions for Chief Robinson and Billy Caldwell, Ouilmette's children, and others but it secured $800 for Ouilmette.
Antoine Ouilmette was "known as a kind, whole souled, generous man of remarkable energy and perseverance, who made friends with everybody, both Indians and whites, and he in turn was universally liked and respected."
In the late 1830s Joseph Fountain of Evanston and others were involved in a legal dispute with Ouilmette, who accused them of trespassing and illegally harvesting timber from the Ouilmette family's reservation. Ouilmette lost the suit and paid a large bill in court costs. Fountain's lawyer sent the sheriff to confiscate and sell two "fine Indian ponies" belonging to Ouilmette, "which were his special pride." It was right after this that the Ouilmette family decided to leave. Shortly after this, in 1838, the Ouilmette family moved to Council Bluffs, where many Potawatomi had previously relocated. He died at Council Bluffs, Iowa on 1 December 1841.
- Wilmette, Illinois (town named for Ouilmette's)
- Stewart, Adam H. "Wilmette, IL". The Electronic Encyclopedia of Chicago. Chicago Historical Society. Retrieved 17 July 2010.
- Grover, Antoine Ouilmette, pp. 4–5
- James A. Clifton, The Prairie People: Continuity and Change in Potawatomi Indian Culture 1665–1965 (Lawrence, Kansas: The Regents Press of Kansas, 1977, ISBN 0-7006-0155-4) p. 231.
- Grover Antoine Ouilmette, p. 4
- "Ouilmette, Antoine Louis". Early Chicago. Early Chicago, Inc. Retrieved 17 July 2010.
- Currey, Josiah Seymour (1912). Chicago: its history and its builders. Volume II. Chicago: The S.J. Clarke Publishing Company. p. 314.
- Schultz, Rime Lunin; Hast, Adele, eds. (2001). Women Building Chicago 1790-1990. Bloomington and Indianapolis, Indiana: Indiana University Press. pp. 653–54. ISBN 978-0-253-33852-5.
- Letter from Antoine Ouilmette to John H. Kinzie dated June 1, 1839, reproduced in Blanchard, Rufus (1898). Discovery and Conquests of the Northwest, with the History of Chicago (volume 1). R. Blanchard and Company. p. 574. Retrieved September 7, 2010.
- Shea, Robert (1987). From No Man’s Land, To Plaza del Lago. 919 N. Michigan Ave., Chicago, IL. 60611: American References Publishing Corporation. p. 15.
- Grover, Antoine Ouilmette, pp. 7–8
- Grover, Antoine Ouilmette, pp. 25
- George D. Bushnell. Wilmettee: A History. (Wilmette, Illinois: Wilmette Bicentennial Commission, 1976), 6.
- Grover, Antoine Ouilmette, pp.9
- Grover, Antoine Ouilmette, pp.14.
- Grover, Antoine Ouilmette, pp. 16.
- Grover, Antoine Ouilmette, pp. 25.
- Grover, Antoine Ouilmette. and Bushnell, Wilmette: a history, pp. 13.
- Grover, Frank R. (1908). Antoine Ouilmette. Evanston Historical Society. Retrieved September 7, 2010.