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Astrophytum caput-medusae (synonym Digitostigma caput-medusae)  is a species of cactus native to Mexico, specifically the state of Nuevo León; the plant is reported to grow wild only at a single location. This species differs from the conventional star-shaped phenotype associated with other Astrophytum members. The plant is characterized by a cylindrical, reduced stem with triangular or cylindrical tubercles producing yellow flowers with orange perianth sections. Propagation by seed, tissue culture or via grafting have all been reported. The species is considered critically endangered by the IUCN due to the plant's limited growth range, destruction by livestock and over collection of wild specimen by plant collectors 
- Gómez-Hinostrosa, C. & Hernández, H.M. (2013). "Astrophytum caput-medusae". IUCN Red List of Threatened Species. Version 2013. International Union for Conservation of Nature. Retrieved 4 November 2018.
- "Astrophytum caput-medusae". www.iucnredlist.org. Retrieved 2017-03-11.
- "Astrophytum caput-medusae". www.cactus-art.biz. Retrieved 2017-03-11.
- "Astrophytum caput-medusae | World of Succulents". World of Succulents. 2015-06-03. Retrieved 2017-03-11.
- Media related to Astrophytum caput-medusae at Wikimedia Commons
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