Jump to content

Autoeczematization

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by MrBill3 (talk | contribs) at 14:25, 14 September 2015 (clean up, added orphan tag using AWB). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Autoeczematization refers to the development of widespread dermatitis or dermatitis distant from a local inflammatory focus.[1]: 81  Autosensitization (autoeczematization or “id” reaction) refers to an acute, pruritic papulovesicular eruption that develops at cutaneous sites distant from a primary focus and is unrelated to the inciting cause of the primary inflammation.[2]

The pathogenesis is not fully understood. One hypothesis is that autoeczematization is due to hyperirritability of the skin induced by immunologic or nonimmunologic stimuli and mediated by epidermal cytokines. Histologic findings are nonspecific and include spongiosis and a dermal lymphohistiocytic infiltrate with eosinophils.[3]

See also

References

  1. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  2. ^ Belsito DV. Autosensitization dermatitis. In: Fitzpatrick's Dermatology in General Medicine, Seventh, Wolff K, Goldsmith Lowell A, Katz SI, et al. (Eds), McGraw Hill Medical, New York, NY 2008. Vol I, p.167.
  3. ^ http://www.uptodate.com/contents/stasis-dermatitis?source=search_result&search=autoeczematization&selectedTitle=5%7E8