B4GALT2

B4GALT2
Identifiers
Aliases	B4GALT2, B4Gal-T2, B4Gal-T3, beta4Gal-T2, beta-1,4-galactosyltransferase 2
External IDs	OMIM: 604013; MGI: 1858493; HomoloGene: 2804; GeneCards: B4GALT2; OMA:B4GALT2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	43,991,170 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	117,740,684 bp
RNA expression pattern
	Top expressed in
	Brodmann area 10; ; amygdala; ; cingulate gyrus; ; anterior cingulate cortex; ; stromal cell of endometrium; ; right frontal lobe; ; apex of heart; ; ganglionic eminence; ; muscle of thigh; ; gastrocnemius muscle;
	Top expressed in
	perirhinal cortex; ; entorhinal cortex; ; superior frontal gyrus; ; primary visual cortex; ; ventricular zone; ; neural layer of retina; ; dentate gyrus of hippocampal formation granule cell; ; ovarian follicle; ; yolk sac; ; CA3 field;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; N-acetyllactosamine synthase activity; galactosyltransferase activity; lactose synthase activity; metal ion binding; glycosyltransferase activity; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;
Cellular component	integral component of membrane; Golgi cisterna membrane; Golgi membrane; membrane; nucleoplasm; Golgi apparatus; intracellular membrane-bounded organelle;
Biological process	protein glycosylation; keratan sulfate biosynthetic process; memory; locomotory behavior; visual learning; cerebellar Purkinje cell layer development; brain development; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	8704
	53418
	ENSG00000117411
	ENSMUSG00000028541
	O60909
	Q9Z2Y2
	NM_030587; NM_001005417; NM_003780
	NM_001253381; NM_017377
	NP_001005417; NP_003771; NP_085076
	NP_001240310; NP_059073
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-1,4-galactosyltransferase 2 is an enzyme that in humans is encoded by the B4GALT2 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000117411 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028541 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Almeida R, Amado M, David L, Levery SB, Holmes EH, Merkx G, van Kessel AG, Rygaard E, Hassan H, Bennett E, Clausen H (Jan 1998). "A family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3". J Biol Chem. 272 (51): 31979–91. doi:10.1074/jbc.272.51.31979. PMID 9405390.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Lo NW, Shaper JH, Pevsner J, Shaper NL (Aug 1998). "The expanding beta 4-galactosyltransferase gene family: messages from the databanks". Glycobiology. 8 (5): 517–26. doi:10.1093/glycob/8.5.517. PMID 9597550.
^ "Entrez Gene: B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2".

References

Further reading