B4GALT5

B4GALT5
Identifiers
Aliases	B4GALT5, B4Gal-T5, BETA4-GALT-IV, beta4Gal-T5, beta4GalT-V, gt-V, beta-1,4-galactosyltransferase 5
External IDs	OMIM: 604016; MGI: 1927169; HomoloGene: 3507; GeneCards: B4GALT5; OMA:B4GALT5 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	49,713,878 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	167,191,103 bp
RNA expression pattern
	Top expressed in
	nasal epithelium; ; palpebral conjunctiva; ; trachea; ; trabecular bone; ; pericardium; ; mucosa of urinary bladder; ; tibialis anterior muscle; ; secondary oocyte; ; pancreatic ductal cell; ; olfactory zone of nasal mucosa;
	Top expressed in
	gastrula; ; yolk sac; ; zygote; ; decidua; ; right kidney; ; proximal tubule; ; tail of embryo; ; genital tubercle; ; secondary oocyte; ; spermatocyte;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	glycosyltransferase activity; transferase activity; galactosyltransferase activity; metal ion binding; beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; N-acetyllactosamine synthase activity; UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity;
Cellular component	integral component of membrane; Golgi cisterna membrane; Golgi membrane; Golgi apparatus; membrane;
Biological process	protein glycosylation; keratan sulfate biosynthetic process; O-glycan processing; carbohydrate metabolic process; poly-N-acetyllactosamine biosynthetic process; ganglioside biosynthetic process via lactosylceramide; central nervous system neuron axonogenesis; central nervous system myelination; regulation of protein stability; positive regulation of embryonic development; neuron maturation; lipid metabolism; sphingolipid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	9334
	56336
	ENSG00000158470
	ENSMUSG00000017929
	O43286
	Q9JMK0
	NM_004776
	NM_019835
	NP_004767
	NP_062809
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-1,4-galactosyltransferase 5 is an enzyme that in humans is encoded by the B4GALT5 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000158470 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000017929 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lo NW, Shaper JH, Pevsner J, Shaper NL (Aug 1998). "The expanding beta 4-galactosyltransferase gene family: messages from the databanks". Glycobiology. 8 (5): 517–26. doi:10.1093/glycob/8.5.517. PMID 9597550.
^ Sato T, Furukawa K, Bakker H, Van den Eijnden DH, Van Die I (Feb 1998). "Molecular cloning of a human cDNA encoding β-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc β-1,4-galactosyltransferase". Proc Natl Acad Sci U S A. 95 (2): 472–7. doi:10.1073/pnas.95.2.472. PMC 18444. PMID 9435216.
^ "Entrez Gene: B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5".

External links

Human B4GALT5 genome location and B4GALT5 gene details page in the UCSC Genome Browser.

References

External links

Further reading