BNC1

BNC1
Identifiers
Aliases	BNC1, BNC, BSN1, HsT19447, basonuclin 1, POF16
External IDs	OMIM: 601930; MGI: 1097164; HomoloGene: 31048; GeneCards: BNC1; OMA:BNC1 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	83,284,664 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	81,642,055 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; parietal pleura; ; gonad; ; hair follicle; ; gingival epithelium; ; secondary oocyte; ; left testis; ; testicle; ; right testis; ; skin of abdomen;
	Top expressed in
	molar; ; primary oocyte; ; secondary oocyte; ; corneal stroma; ; zygote; ; hair follicle; ; endocardial cushion; ; abdominal wall; ; atrioventricular valve; ; trigeminal ganglion;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; metal ion binding; DNA binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; nucleus; nucleoplasm; intracellular membrane-bounded organelle;
Biological process	regulation of transcription, DNA-templated; positive regulation of cell population proliferation; transcription, DNA-templated; epidermis development; spermatogenesis; cell differentiation; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	646
	12173
	ENSG00000169594
	ENSMUSG00000025105
	Q01954
	O35914
	NM_001301206; NM_001717
	NM_007562
	NP_001288135; NP_001708
	NP_031588
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein basonuclin-1 is a protein that in humans is encoded by the BNC1 gene.^[5]^[6]

Template:PBB Summary

BNC1 or Basonuclin 1 does not interact with PICK1. This suggestion that is does is based on the article that proved that PICK1 interacts with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1). Both Basonuclin 1 and brain Na+ channel 1 have the same abbreviation BNC1, but they are not similar proteins and PICK1 interacts with the second protein, not the first one.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000169594 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025105 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tseng H, Green H (Dec 1992). "Basonuclin: a keratinocyte protein with multiple paired zinc fingers". Proc Natl Acad Sci U S A. 89 (21): 10311–5. doi:10.1073/pnas.89.21.10311. PMC 50328. PMID 1332044.
^ "Entrez Gene: BNC1 basonuclin 1".

References

Further reading